Approach to the diabetic with proteinuria

Raman, Gowri; Lee, H A

doi:10.1002/pdi.1960030106

Cited by 1 publication

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“…It is often advised that early morning urine specimens should be screened for proteinuria as they are more concentrated (Pryor, 1977;Raman and Lee, 1986). However, proteinuria may be increased by the upright position (King, 1957) and urine protein concentration is higher during ambulation even when adjusted for creatinine concentration (Ginsberg et af., 1983).…”

Section: Discussionmentioning

confidence: 99%

“…It is often advised that screening for proteinuria with dipsticks should be performed on early morning urine samples because they are more concentrated (Pryor, 1977;Raman and Lee, 1986), but ambulation can increase protein excretion in normal subjects and in patients with proteinuria (King, 1957). We studied protein concentration and dipstick readings in early morning and in random daytime urine samples.…”

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confidence: 99%

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Which Urine Sample for Detection of Proteinuria?

Risdon

Shaw

1989

British Journal of Urology

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The standard practice of screening for proteinuria in the concentrated early morning urine was examined. Protein concentration and dipstick readings were determined in early morning and daytime urines of 56 normal subjects and 110 patients with proteinuria attending a renal clinic. In normal subjects the protein concentration was similar in both urine samples and dipsticks gave the same frequency of false positive results, usually only trace positive. The protein concentration was higher in the daytime urine in 76% of patients. Dipstick readings were similar in 64.5% but higher in the daytime urine in 31% and in the early morning urine in only 4.5%. It is recommended that daytime urine should be screened for proteinuria in patients presenting in out-patient clinics.

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%