Abstract:A straightforward strategy for constructing seven-membered
carbocycles
by employing a Lewis acid catalyzed intramolecular Michael addition
of allenones is reported. It offers atom-economic access to synthetically
important furan-fused bi- or tricyclic frameworks containing seven-membered
carbocycles, which are widely found in natural products possessing
various bioactivities. A number of seven-membered carbocycle-containing
polycyclic frameworks bearing diverse functional groups were prepared
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