Approach to restless leg syndrome in hemodialysis patients

Abstract

Restless legs syndrome (RLS) is an uncomfortable urge to move the legs while the person is at rest. This movement disorder is one of the problems that may develop in the follow-up of hemodialysis patients. It is important to recognize and treat these problems because they are closely related to mortality and morbidity. It is estimated that RLS symptoms occur in 3% of the adult population worldwide and in approximately 27% of hemodialysis patients. Although the pathophysiology of the disease and its relationship with its high prevalence in dialysis patients have not yet been clearly elucidated, it is predicted that pathologies such as central dopamine metabolism disorders, iron deficiency and uremia may underlie the disease. There are some pharmacological and non-pharmacological treatment methods developed based on available data. Current data in the literature regarding the effectiveness and superiority of these treatments are insufficient to clarify the treatment approach. Studies on the subject continue and the unknowns in treatment and pathophysiology are being clarified day by day.