“…However, if hypertension acts as a mechanical factor with deleterious consequences on the arterial wall, the totality of the blood pressure curve should be considered to evaluate the risk (Erbel et al, 2014). Recent fi ndings in hypertensive populations ilustrate that increased pulse pressure is an independent predictor of myocardial infarction, congestive heart failure and cardiovascular death, even in hypertensive patients undergoing successful antihypertensive drug therapy; and also increased aortic pulse wave velocity is an independent predictor of cardiovascular mortality in individuals with essential hypertension (Bhatt et al, 2006;Iurciuc et al, 2011;Iurciuc et al, 2017). Currently, increased pulse pressure and increased pulse wave velocity may be considered either as simple markers of an underlying vascular disease or as strong cardiovascular risk factors.…”
Section: Discussionmentioning
confidence: 99%
“…Arterial stiff ness and wave refl ection are now well accepted as the most important determinants of increasing systolic and pulse pressures in aging societies, thus aff ording a major contribution to stroke and myocardial infarction (Amaricai & Poenaru, 2015;Iurciuc et al, 2017;Mancia, 2007). A major reason for measuring arterial stiff ness in hypertensive patients comes from the demonstration that arterial stiff ness has a predictive value for cardiovascular events, beyond classical cardiovascular risk factors (Iurciuc et al, 2011;Iurciuc et al, 2010). Aortic stiff ening also gives direct evidence of target organ damage, and improves the determination of the overall cardiovascular risk of asymptomatic hypertensive subjects (Volpe et al, 2012).…”
to Score risk calculating led to an increase of the proportion of patients at high risk (from 5 to 15%,P < 0.001).The following results have been found: SCORE risk =5.65 (SD=+/-6.05);PWV=9.2m/s (SD=+/-1.94). Our results confi rm that determining aortic PWV is an usefultool for Primary Practice, as it correlateswith SCORE index,which is recommended by the European Society of Cardiology as an evaluationmethod of cardiovascular risk in patients.
“…However, if hypertension acts as a mechanical factor with deleterious consequences on the arterial wall, the totality of the blood pressure curve should be considered to evaluate the risk (Erbel et al, 2014). Recent fi ndings in hypertensive populations ilustrate that increased pulse pressure is an independent predictor of myocardial infarction, congestive heart failure and cardiovascular death, even in hypertensive patients undergoing successful antihypertensive drug therapy; and also increased aortic pulse wave velocity is an independent predictor of cardiovascular mortality in individuals with essential hypertension (Bhatt et al, 2006;Iurciuc et al, 2011;Iurciuc et al, 2017). Currently, increased pulse pressure and increased pulse wave velocity may be considered either as simple markers of an underlying vascular disease or as strong cardiovascular risk factors.…”
Section: Discussionmentioning
confidence: 99%
“…Arterial stiff ness and wave refl ection are now well accepted as the most important determinants of increasing systolic and pulse pressures in aging societies, thus aff ording a major contribution to stroke and myocardial infarction (Amaricai & Poenaru, 2015;Iurciuc et al, 2017;Mancia, 2007). A major reason for measuring arterial stiff ness in hypertensive patients comes from the demonstration that arterial stiff ness has a predictive value for cardiovascular events, beyond classical cardiovascular risk factors (Iurciuc et al, 2011;Iurciuc et al, 2010). Aortic stiff ening also gives direct evidence of target organ damage, and improves the determination of the overall cardiovascular risk of asymptomatic hypertensive subjects (Volpe et al, 2012).…”
to Score risk calculating led to an increase of the proportion of patients at high risk (from 5 to 15%,P < 0.001).The following results have been found: SCORE risk =5.65 (SD=+/-6.05);PWV=9.2m/s (SD=+/-1.94). Our results confi rm that determining aortic PWV is an usefultool for Primary Practice, as it correlateswith SCORE index,which is recommended by the European Society of Cardiology as an evaluationmethod of cardiovascular risk in patients.
“…In individuals who are not pregnant, arterial stiffness typically intensifies as one moves from the aorta to the peripheral arteries, which is essential for minimizing the energy carried by the forward wave to the microcirculation [6]. Over the years, many studies have associated the severity and occurrence of arterial stiffness with various pathologies with cardiovascular impact [7] or even with health outcomes on longer-term follow-up [8]. Studies have shown that aortic stiffness is consistently elevated in pregnancy-associated hypertension compared to healthy pregnant women [9].…”
Introduction: In developed countries, heart disease is the primary cause of maternal mortality during pregnancy. Arterial stiffness, an independent risk factor for atherosclerosis and a predictor of cardiovascular complications, can be assessed using the augmentation index (AIx) and pulse wave velocity (PWV). In this prospective study, we aimed to evaluate diverse hemodynamic parameters and arterial stiffness in pregnant women before and after participating in a structured, personalized exercise training program. Materials and methods: Forty healthy pregnant women, non-smokers, who agreed to participate daily for 12 weeks in a physical exercise training program under the supervision of a team made up of an obstetrician, a cardiologist, and a physiotherapist were included. Anthropometric characteristics, arterial function, and physical activity data were collected from the participants at two different time points: at the beginning of the exercise training program (T0) and at the end, after 12 weeks (T1). Results: Upon conducting a statistical analysis, it was discovered that there were noteworthy disparities (p = 0.05) in body mass index, brachial AIx, systolic blood pressure, and pulse pressure values between the two time points. The regression analysis for the AIx brachial values and the PWVao values from Trim II (T0) and Trim III (T1) showed major differences between these two time points; the association between the AIx brachial values in the second and third trimesters of pregnancy revealed a strong direct significant correlation (p < 0.001), and the correlation between the PWVao values in the second (T0) and third trimester (T1) of pregnancy was weak and insignificant (p = 0.12). Conclusions: The findings of our study indicate that a personalized exercise training program positively impacts the physical and psychological well-being of pregnant women, leading to a reduction in PWV.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.