Approach to giant cell arteritis and recent evidence on its relation with cardiovascular risk. A review

Crespo, Rui Gustavo; Falcão, Luiz Menezes

doi:10.1016/j.eurger.2016.06.003

Cited by 6 publications

(3 citation statements)

References 43 publications

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“…Also, FDG-PET/CT has a major role in assessing the extent of disease. 20 Previous western population studies have shown that GCA is present in 16%–21% of PMR patients. 11 However, in epidemiology studies on PMR patients within the Korean population, no GCA cases were reported.…”

Section: Discussionmentioning

confidence: 98%

Characteristics of Korean Patients with Polymyalgia Rheumatica: a Single Locomotive Pain Clinic Cohort Study

2018

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BackgroundPolymyalgia rheumatica (PMR) is a common systemic inflammatory disease of the elderly; however, the clinical characteristics and therapeutic response of PMR in Korea have been rarely studied.MethodsWe reviewed the medical records of 54 Korean patients diagnosed with PMR between January 2009 and February 2017 in a locomotive pain clinic of one tertiary referral hospital. We analyzed epidemiologic and clinical characteristics, therapeutic responses, and prognostic factors for remission-failure at one-year after oral prednisolone treatment.ResultsIn 54 patients with PMR, 32 (59.3%) were female. The average age at diagnosis was 65.0 ± 10.5 years. Duration of symptoms before diagnosis was 8.1 ± 8.6 months. All patients had shoulder pain (54 patients, 100.0%); 49 patients (90.7%) had hip girdle pain, while 19 patients (35.2%) had peripheral joint pain. Four patients (7.4%) were accompanied by the giant cell arteritis (GCA). There was no seasonal preference for symptom development. Only 19 patients were diagnosed with PMR at initial symptom presentation. At one-year follow-up after oral prednisolone treatment, the remission rate was 35.3% (12/34). Multivariate analysis showed that history of relapse (odds ratio, 6.81; 95% confidence interval, 1.035–44.804) was a significant predictor of remission-failure.ConclusionThe rate of remission (35.3%) after oral prednisolone treatment was similar to previous reports in western countries; and GCA is not a rare condition in Korean PMR patients. Misdiagnosis of PMR is common, and heightened consideration for PMR is needed in elderly patients who present inflammatory features of bilateral shoulder pain.

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Section: Discussionmentioning

confidence: 98%

Characteristics of Korean Patients with Polymyalgia Rheumatica: a Single Locomotive Pain Clinic Cohort Study

2018

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“…Unfortunately, the patient died two months following discharge from myocardial infarction. Studies reported an increased mortality in the first two years following diagnosis, but not with longer follow up [19,20]. The main causes of death are diseases of the circulatory system: myocardial infarction, aortic aneurysm, stroke [19].…”

Section: Discussionmentioning

confidence: 99%

“…Studies reported an increased mortality in the first two years following diagnosis, but not with longer follow up [19,20]. The main causes of death are diseases of the circulatory system: myocardial infarction, aortic aneurysm, stroke [19]. Prognosis depends on the precocity of establishing treatment and on the severity of symptoms upon presentation.…”

Section: Discussionmentioning

confidence: 99%

Bilateral irreversible visual loss due to arteritic anterior optic ischemic neuropathy

Damian¹

2022

Case Rep Int

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Introduction:Anterior optic ischemic neuropathy (AOIN) is the most frequent cause of visual loss in giant cell arteritis (GCA). As blindness is rarely reversible, the main therapeutic goal is to prevent bilateral disease by immediate initiation of high-dose intravenous steroids. Approximately, one third of patients present with bilateral visual impairment. Case Report: A 77-year-old patient, came to the Ophthalmology Emergency Room for sudden loss of vision in the left eye (OS) to no light perception (NLP) with two days duration and significant narrowing of the visual field in the right eye (OD) with 10 hours duration. Fundus examination revealed swelling and pallor of the optic disc in both eyes (OU). Laboratory examination showed elevated ESR (56 mm/h) and CRP (5.24 mg/dl). Temporal artery biopsy (TAB) proved granulomas and fibrosis within the vessel wall. Immediate Methylprednisolon 1 gm was administered intravenously for five days, followed by oral Prednisone 1mg/kg for four weeks with tapering of 10 mg per month. The patient was put on diabetic and low sodium regimen. During the 3rd day of treatment, vision OD dropped to NLP. Despite continuing systemic steroid therapy, vision remained

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Improving diagnosis and prognosis in giant cell arteritis: Still more issues than answers

Liozon

2017

European Geriatric Medicine

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Approach to giant cell arteritis and recent evidence on its relation with cardiovascular risk. A review

Cited by 6 publications

References 43 publications

Characteristics of Korean Patients with Polymyalgia Rheumatica: a Single Locomotive Pain Clinic Cohort Study

Characteristics of Korean Patients with Polymyalgia Rheumatica: a Single Locomotive Pain Clinic Cohort Study

Bilateral irreversible visual loss due to arteritic anterior optic ischemic neuropathy

Improving diagnosis and prognosis in giant cell arteritis: Still more issues than answers

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