Appraising efficacy of existing and advanced technologies for the remediation of beta-blockers from wastewater: A review

Ahmad, Azhan; Priyadarshini, Monali; Raj, Rishabh; Das, Sovik; Ghangrekar, Makarand M.

doi:10.1007/s11356-021-18287-4

Cited by 9 publications

(3 citation statements)

References 165 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several anti-neoplastic drugs also induce teratogenicity among aquatic life forms along with damage to several organ systems and disruption of cellular machinery (Wormington et al, 2020). Recalcitrant contaminants like beta blockers induce cardiac toxicity along with reproductive toxicity across various aquatic life forms (Ahmad et al, 2022). Rising use of antibiotics by humans has led to their (Seki et al, 2004) Trenbolone esters Fathead Minnow Reproductive system disruption and toxicity (Ankley et al, 2003;Jensen et al, 2006;Quinn et al, 2007) Japanese Quail…”

Section: Pharmaceutical Drugs: a Boon To Humans But A Bane For The En...mentioning

confidence: 99%

Aptasensors in environmental forensics: Tracking the silent killers

Dube

Satish

Rawtani

2023

WIREs Forensic Science

View full text Add to dashboard Cite

Since its inception, environmental forensics has observed expansion of its horizons across several threats to life forms, be it pertaining to wildlife trafficking or tracking the release of effluents containing pharmaceutical drugs, toxins, pesticides, heavy metals, pathogenic microbes, and microplastics. With the substantial growth of pharmaceutical industry over the past few decades, especially with respect to therapeutic personal care products and over the counter drugs, a new threat to environment has emerged from pharmaceutical toxicity.Due to the recalcitrant nature and poor wastewater treatment practices related to these pollutants, they leach into different strata of ecosystem like aquatic, terrestrial, and atmospheric systems. These drugs pose a threat to several life forms even at trace concentrations. This article aims at providing a profound perspective by exhaustively reviewing several classes of pharmaceutical drugs that are silently threatening the wildlife and environment. The sensitive, specific, and rapid detection of such drugs menacing the environment and wildlife is pertinent and can be achieved through aptamer-based biosensors known as aptasensors. These are a rising class of biosensors with vast application potential in numerous fields including environmental and wildlife forensics. This article also highlights the gap in research in the availability of rapid sensors for trace detection of drugs in environment hence encouraging researchers to explore the under-explored potential of aptasensors in environmental forensics. Highly sensitive and selective detection of such drugs is crucial in narrowing down the origin of such pollutants so as to aid the regulatory authorities in enforcing control over their release into environment.

show abstract

Section: Pharmaceutical Drugs: a Boon To Humans But A Bane For The En...mentioning

confidence: 99%

Aptasensors in environmental forensics: Tracking the silent killers

Dube

Satish

Rawtani

2023

WIREs Forensic Science

View full text Add to dashboard Cite

show abstract

“…[3] Among pharmaceuticals, β-blockers have been widely detected in various environmental water matrices at amounts ranging from ng L À 1 to μg L À 1 . [4] The low biodegradability and high water solubility of β-blockers have encouraged their ubiquitous fate in the environment. [5] The health impacts related to the fate of β-blockers in the environment include the disruption of testosterone levels, reduction of fertility and reproduction rates, and reduction of spermatozoid mobility of fish.…”

Section: Introductionmentioning

confidence: 99%

“…Therefore, they have been detected in groundwater, surface water, lake water, effluents and drinking waters [3] . Among pharmaceuticals, β‐blockers have been widely detected in various environmental water matrices at amounts ranging from ng L −1 to μg L −1 [4] . The low biodegradability and high water solubility of β‐blockers have encouraged their ubiquitous fate in the environment [5] .…”

Section: Introductionmentioning

confidence: 99%

Adsorption Isotherms and Kinetics of Acebutolol and Metoprolol on Magnetic Nanocomposite Fe₃O₄@MIL‐101(Cr)

Waleng,

Selahle,

Jakavula

et al. 2023

ChemistrySelect

View full text Add to dashboard Cite

Contamination of water bodies by emerging pollutants such as β‐blockers has been a global concern over the past few years. This is due to the bioaccumulative character of β‐blockers in the aquatic systems, and their excessive usage might cause adverse effects on both humans and aquatic biota. A reusable and recyclable magnetic chromium‐based MIL‐101 (Fe3O4@MIL‐101(Cr)) nanocomposite was used as an adsorbent for the removal of the selected β‐blockers (acebutolol and metoprolol) from wastewater. The nanocomposite‘s structural, magnetic and surface properties were confirmed using various characterisation techniques. The equilibrium data indicated that the maximum adsorption capacities of Fe3O4@MIL‐101(Cr) for acebutolol and metoprolol were 30.9 mg g−1 and 28.3 mg g−1, respectively. The isotherm and kinetic experimental data best fitted Langmuir isotherm and pseudo‐second‐order kinetics models. Obtained free energies using the Dubinin‐Radushkevich model were above 8 kJ mol−1, demonstrating that the interaction mechanism between β‐blockers and the Fe3O4@MIL‐101(Cr) nanocomposite was chemisorption. The prepared nanocomposite was then used to remove β‐blockers from real samples, and maximum removal efficiencies (94.1–97.1 %) were obtained in the presence of co‐existing species. The Fe3O4@MIL‐101(Cr) hybrid showed great potential for efficient and facile removal of β‐blockers from river water, effluent and influent wastewater samples.

show abstract

Contaminants of emerging concerns (CECs) in a municipal wastewater treatment plant in Indonesia

Astuti

Notodarmojo

Priadi

et al. 2022

Environ Sci Pollut Res

View full text Add to dashboard Cite

This study provides the first set of quantitative data on the occurrence and fate of a wide range of contaminants of emerging concerns (CECs) in Indonesia’s largest wastewater treatment plant (WWTP). The WWTP employs waste stabilization ponds (WSPs) as the secondary treatment before discharging the effluent to the Citarum River. Fourteen out of twenty-two monitored CECs were detected in the wastewater influent, and seven were present in the effluent, with a total concentration of 29.8 ± 0.4 µg/L and 0.5 ± 0.0 µg/L, respectively. The occurrence of the CECs in this study was found to be well correlated with their possible use and known detection in surface waters in Indonesia. Caffeine (CAF) at 12.2 ± 0.1 µg/L, acetaminophen (ACT) at 9.1 ± 0.1 µg/L, N,N-diethyl-m-toluamide (DEET) at 5.0 ± 0.1 µg/L, ibuprofen (IBU) at 2.3 ± 0.0 µg/L, and triclosan (TCS) at 470 ± 64 ng/L were discovered as the five most prevalent CECs, followed by bisphenol A (BPA), trimethoprim (TMP), Tris(2-chloroethyl) phosphate (TCEP), sulfamethazine (SMZ), carbamazepine (CBZ), fluoxetine (FLX), benzotriazole (BTA), sulfamethoxazole (SMX), and metformin (METF). Biodegradable CECs (SMX, SMZ, ACT, IBU, TCS, BPA, CAF, DEET, and TMP) were efficiently removed (83–100%) by the WSP. In contrast, recalcitrant CECs achieved poor removal efficiencies (e.g., FLX at 24%), and for others, treatment processes even resulted in elevated concentrations in the effluent (CBZ by 85%, TCEP by 149%, and BTA by 92%). The CECs’ influent concentrations were determined to pose a moderate aquatic cumulative risk, while no such risk was associated with their effluent concentrations. The study demonstrates the importance of conventional WWTPs in reducing the concentrations of CECs to minimize their aquatic contamination risk. The findings are relevant for countries, such as Indonesia, with limited resources for advanced centralized wastewater treatments, and which are exploring the efficacy of centralized WSP against the existing decentralized treatments.

show abstract

Appraising efficacy of existing and advanced technologies for the remediation of beta-blockers from wastewater: A review

Cited by 9 publications

References 165 publications

Aptasensors in environmental forensics: Tracking the silent killers

Aptasensors in environmental forensics: Tracking the silent killers

Adsorption Isotherms and Kinetics of Acebutolol and Metoprolol on Magnetic Nanocomposite Fe₃O₄@MIL‐101(Cr)

Contaminants of emerging concerns (CECs) in a municipal wastewater treatment plant in Indonesia

Contact Info

Product

Resources

About

Appraising efficacy of existing and advanced technologies for the remediation of beta-blockers from wastewater: A review

Cited by 9 publications

References 165 publications

Aptasensors in environmental forensics: Tracking the silent killers

Aptasensors in environmental forensics: Tracking the silent killers

Adsorption Isotherms and Kinetics of Acebutolol and Metoprolol on Magnetic Nanocomposite Fe3O4@MIL‐101(Cr)

Contaminants of emerging concerns (CECs) in a municipal wastewater treatment plant in Indonesia

Contact Info

Product

Resources

About

Adsorption Isotherms and Kinetics of Acebutolol and Metoprolol on Magnetic Nanocomposite Fe₃O₄@MIL‐101(Cr)