Appraisal of immediate and late effects of mobile phone radiations at 2100 MHz on mitotic activity and DNA integrity in root meristems of Allium cepa

Chandel, Shikha; Kaur, Shalinder; Issa, Mohd; Singh, Harminder Pal; Batish, Daizy R.; Kohli, R. K.

doi:10.1007/s00709-019-01386-y

Cited by 16 publications

(1 citation statement)

References 42 publications

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“…The genotoxicological evaluation showed that the majority of the tested compounds (84/90, 93%) induced significant DNA damage in a dose‐dependent manner, while a small fraction of them (4/90, 5%) showed genotoxicity only at the highest dose: the herbicide 2,4‐dichlorophenoxyacetic acid at 4.02 mg/L (Özkul et al, 2016), the multiwalled carbon nanotubes at 10 μg/mL (Ghosh et al, 2015a), the electromagnetic field radiations at 2100 MHz for 4 h (Chandel et al, 2019a) and the 500 mg/L‐methyl orange contaminated water (Alaguprathana et al, 2022). Only two compounds (2%) were found to be non‐genotoxic: the organic molecule pyroligneous acid at concentration ranging from 0.005% to 3% (Sivaram et al, 2022) and the hematite nanoparticles at 20, 60, and 100 mg/L (Rath et al, 2020), both tested on onion bulbs (Figure 6).…”

Section: Resultsmentioning

confidence: 99%

A scoping review of recent advances in the application of comet assay to Allium cepa roots

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Zerbini

Feretti

2023

Environ and Mol Mutagen

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The comet assay is a sensitive method for the evaluation of DNA damages and DNA repair capacity at single‐cell level. Allium cepa is a well‐established plant model for toxicological studies. The aim of this scoping review was to investigate the recent application of the comet assay in Allium cepa root cells to assess the genotoxicity. To explore the literature a search was performed selecting articles published between January 2015 and February 2023 from Web of Science, PubMed, and Scopus databases using the combined search terms “Comet assay” and “Allium cepa”. All the original articles that applied the comet assay to Allium cepa root cells were included. Of the 334 records initially found, 79 articles were identified as meeting the inclusion criteria. Some studies reported results for two or more toxicants. In these cases, the data for each toxicant were treated separately. Thus, the number of analyzed toxicants (such as chemicals, new materials, and environmental matrices) was higher than the number of selected papers and reached 90. The current use of the Allium‐comet assay seems to be directed towards two types of approach: the direct study of the genotoxicity of compounds, mainly biocides (20% of analyzed compounds) and nano‐ and microparticles (17%), and assessing a treatment's ability to reduce or eliminate genotoxicity of known genotoxicants (19%). Although the genotoxicity identified by the Allium‐comet assay is only one piece of a larger puzzle, this method could be considered a useful tool for screening the genotoxic potential of compounds released into the environment.

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