Apport actuel des D-dimères dans le diagnostic d'exclusion de la maladie thromboembolique veineuse

Siméon, D.; Petitot, L; Martelet, Michele; Mouallem, J; Bombarde, A

doi:10.1016/s0923-2532(00)86667-3

Cited by 3 publications

(2 citation statements)

References 33 publications

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“…Indeed, the clinical diagnosis is particularly difficult because of the low sensitivity and specificity of the clinical manifestations and many complementary examinations, notably phlebography in DVT and angiography in PE, which are invasive and carry a risk of morbidity and mortality. Other less invasive exams that often allow them to be overlooked; the venous Doppler ultrasonography in DVT, helical CT and pulmonary scintigraphy in PE; which are not always easily accessible for all care facilities and require significant infrastructure in terms of equipment and staff [14].…”

Section: Discussionmentioning

confidence: 99%

Interest of the D-dimers Assay in the Medical Care of Thromboembolic Disease: Experience of the Hematology Laboratory of the Military Hospital Avicenne of Marrakech

Mouamin¹,

Allali²,

Boufrioua³

et al. 2019

AJBLS

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The objective of our study is to show the benefits of D-dimers (DD) dosing in the diagnostic care of thromboembolic disease. A retrospective study conducted over a 2-year period (2016)(2017), including all DD dosing requests sent to the hematology laboratory at the Avicenne Military Hospital, excluding patients under 18 years of age. The quantitative assay was performed by an immunoturbidimetric method on STA Compact automaton, (STAGO), with STA®-Liatest® D-Di reagents with respect for the pre-analytical phase. We collected 100 samples over the study's two year period. The requests mainly came from the emergencies and polyvalent intensive care unit. The clinical picture suggested a deep vein thrombosis in 56% of cases and pulmonary embolism in 44% of cases. The search was positive in 78% of cases. Sensitivity and negative predictive value were 100%. Specificity in the ambulatory population was 66.66% vs 28% in the hospital population and also decreased with age.

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Section: Discussionmentioning

confidence: 99%

Interest of the D-dimers Assay in the Medical Care of Thromboembolic Disease: Experience of the Hematology Laboratory of the Military Hospital Avicenne of Marrakech

Mouamin¹,

Allali²,

Boufrioua³

et al. 2019

AJBLS

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show abstract

“…En effet, chez les patients de plus de 70 ans sans MTEV, le taux moyen de D-dimères est fréquemment supérieur à 500 μg/ml [5]. Donc, la rentabilité des D-dimères pour exclure le diagnostic de MTEV passe de plus de 50 % chez les moins de 70 ans à moins de 23 % chez les plus de 70 ans et jusqu'à moins de 10 % chez les plus de 90 ans [6].…”

Section: Chez Le Patient âGéunclassified

Intérêts et limites des biomarqueurs dans la prise en charge des patients âgés aux urgences

Bokobza

2011

cah. année gerontol.

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A quelles tranches d'âge s'adresse le dosage des D-dimères ?

Petitot¹,

Siméon²,

Bombarde³

2000

Immuno-analyse & Biologie Spécialisée

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Apport actuel des D-dimères dans le diagnostic d'exclusion de la maladie thromboembolique veineuse

Cited by 3 publications

References 33 publications

Interest of the D-dimers Assay in the Medical Care of Thromboembolic Disease: Experience of the Hematology Laboratory of the Military Hospital Avicenne of Marrakech

Interest of the D-dimers Assay in the Medical Care of Thromboembolic Disease: Experience of the Hematology Laboratory of the Military Hospital Avicenne of Marrakech

Intérêts et limites des biomarqueurs dans la prise en charge des patients âgés aux urgences

A quelles tranches d'âge s'adresse le dosage des D-dimères ?

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