With rapid advancements in radiotherapy technology, the complexity of the radiotherapy treatment has multiplied over the past few decades. As a result, it has become increasingly difficult for radiotherapists to have a clear and logical overview of the system state during treatment delivery. Any consequent mishaps may result in serious harm to the patient. To address this concern, a novel radiotherapy control and monitoring interface which visualizes complex relationships and constraints within the treatment system may help radiotherapists understand and address any issues that may arise during radiotherapy delivery. As such, Ecological Interface Design (EID) was applied to redesign the user interface used during radiotherapy delivery. A literature review, ethnographic observations, and domain expert feedback were used to establish a work domain model of the radiotherapy system. From the work domain model, information requirements for interface design were extracted. Some of these requirements suggest the need for novel graphic elements which incorporate multiple treatment parameters for more integrated overviews of the system state. The results from the analysis will be used in the subsequent design phase, which will be aimed at designing a more effective radiotherapy monitoring user interface for improved patient safety.