“…The DWI/Apparent Diffusion Coefficient (ADC) lesions of all patients were matched with their clinical stroke manifestations. Clinical data were collected, including demographic data (sex, age, admission National Institutes of Health Stroke Scale (NIHSS), and time of admission) and risk factors (hypertension 7 , diabetes 8 , coronary artery disease 9 , dyslipidemia, smoking history, and drinking History), as defined in previous reports 10 . The determination of ICAS was based on ancillary examinations such as cranial magnetic resonance angiography (MRA), computerized tomography angiography (CTA) or digital subtraction angiography (DSA), and the stenosis rate = (1 - stenosis diameter/normal diameter).…”