Applying new approach methodologies to assess next-generation tobacco and nicotine products
David Thorne,
Damian McHugh,
Liam Simms
et al.
Abstract:In vitro toxicology research has accelerated with the use of in silico, computational approaches and human in vitro tissue systems, facilitating major improvements evaluating the safety and health risks of novel consumer products. Innovation in molecular and cellular biology has shifted testing paradigms, with less reliance on low-throughput animal data and greater use of medium- and high-throughput in vitro cellular screening approaches. These new approach methodologies (NAMs) are being implemented in other i… Show more
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