Applications of the Excimer Laser

Beggs, Sarah; Short, J G; Rengifo‐Pardo, Mónica; Ehrlich, Alison

doi:10.1097/dss.0000000000000485

Cited by 52 publications

(52 citation statements)

References 58 publications

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“…Examples include new topical medications for acne, biologics and excimer laser for psoriasis, checkpoint inhibitors for melanoma, and oral and systemic treatments for cutaneous lymphoma. 49,[58][59][60][61][62] Since 2013, costs of many widely used dermatologic medications have increased significantly, and better understanding of the pathophysiology of diseases has led to development of new medications. Therefore, the health care cost of skin disease at the time of writing this article most likely surpasses this 2013 estimation.…”

Section: Discussionmentioning

confidence: 99%

The burden of skin disease in the United States

Lim

Collins²,

Resneck

et al. 2017

Journal of the American Academy of Dermatology

382

309

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Since the publication of the last US national burden of skin disease report in 2006, there have been substantial changes in the practice of dermatology and the US health care system. These include the development of new treatment modalities, marked increases in the cost of medications, increasingly complex payer rules and regulations, and an aging of the US population. Recognizing the need for up-to-date data to inform researchers, policy makers, public stakeholders, and health care providers about the impact of skin disease on patients and US society, the American Academy of Dermatology produced a new national burden of skin disease report. Using 2013 claims data from private and governmental insurance providers, this report analyzed the prevalence, cost, and mortality attributable to 24 skin disease categories in the US population. In this first of 3 articles, the presented data demonstrate that nearly 85 million Americans were seen by a physician for at least 1 skin disease in 2013. This led to an estimated direct health care cost of $75 billion and an indirect lost opportunity cost of $11 billion. Further, mortality was noted in half of the 24 skin disease categories.

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Section: Discussionmentioning

confidence: 99%

The burden of skin disease in the United States

Lim

Collins²,

Resneck

et al. 2017

Journal of the American Academy of Dermatology

382

309

View full text Add to dashboard Cite

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“…Excimer lasers have been studied the most, which is thought to cause hair regrowth by inducing apoptosis of T cells, 19 as AA is known to be a T cell mediated disorder. 15 Other lasers that have been studied include erbium glass laser, Nd: YAG laser, fractional CO2 laser, and LLLT, which have used based on the findings of paradoxical hypertrichosis and hair growth upon wound healing.…”

Section: Resultsmentioning

confidence: 99%

“…18,19 The pathophysiology underlying excimer lasers that induce the therapeutic effects in AA are thought to be different from that of other lasers. Although the exact mechanism is unclear, excimer laser is thought to induce apoptosis of T cells, thereby leading to therapeutic effects in inflammatory diseases, such as psoriasis.…”

Section: -Nm Excimer Lasermentioning

confidence: 99%

Use of Lasers in the Treatment of Alopecia Areata

Chu

Kim

2016

Medical Lasers

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Alopecia areata (AA) is a complex autoimmune disease characterized by round or oval patches of non-scarring hair loss that is mediated by lymphocytes affecting the hair follicles. To treat localized AA, intralesional corticosteroid injections and topical corticosteroids are most commonly used, while for widespread AA, systemic steroids, immunosuppresants, and contact immunotherapy are commonly considered. However, therapeutic options for refractory AA that is unresponsive to these conventional treatments are limited. Various lasers have been suggested in recent studies to treat AA. The effect of 308-nm excimer laser was the most studied, while others, including neodymium-doped yttrium aluminum garnet, erbium:glass laser, fractional CO2 laser, and low-level laser therapy, have also been assessed. Despite the nascent state of research on lasers as a treatment option for AA, there have been a great deal of promising results. It is possible for lasers to become the mainstay treatment option of AA. Key words

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“…Ancak, yayınlar çok sınırlı sayıda ve kalitesi göz önüne alındığında, lazer, şu anda AD'nin tedavisi için tavsiye edilmez 107 . Ekstrakorporeal fototerapi şiddetli ve eritrodermik AD'nin şiddetini ve semptomları kontrol altına alma amacı ile kullanılmaktadır.…”

Section: Lazerler Ve Ekstrakorporeal Fototerapiunclassified