Applications of Polysaccharides in Nutrition and Medicine

Citric acid cross-linking of a hydrogel from Aloe vera (Aloe barbadensis M.) engenders a pH-responsive, superporous, and smart material for drug delivery

“…Aer certain periods, the tea-bags holding the swelled CL-ALH were removed from the beakers, and the excess swelling media were drained. The tea-bag was weighed accurately and the swelling capacity was calculated using eqn (1). The swelling of CL-ALH was studied till equilibrium, i.e., 300 min.…”

“…Aer adding 100 mg of CL-ALH to the tea-bag, it was hung upside down in a beaker containing 100 mL of swelling medium, i.e., pH 7.4, and allowed to expand for 1 h. The weight of the tea-bag was determined using eqn (1) aer every 15 min. Aer 1 h of studying the effects of swelling, the same tea-bag was placed in a different beaker (100 mL) that contained a deswelling medium, i.e., pH 1.2, and it was le to deswell for 1 h. Aer waiting for 15 min., the tea bag was removed and its ability to deswell was determined using eqn (1). This cycle of swelling/deswelling was performed a total of four times.…”

“…Naturally occurring plant-based materials are catching the eyes of many researchers for their utilization in the biomedical eld day by day owing to their non-toxicity, biocompatibility, biodegradability, non-hemolytic, and non-immunogenicity. [1][2][3][4] These polysaccharides have many functional groups which are being used for physical and chemical cross-linking. 5,6 Through cross-linking, the physical and chemical properties of polysaccharides are tuned to get desired results or applications.…”