Applications of photoacoustic spectroscopy and imaging in gastroenterology

Thakur, Surya N.; Pandey, Durgatosh; Shachindra, N.

doi:10.1016/b978-0-323-91732-2.00001-x

Cited by 2 publications

(1 citation statement)

References 48 publications

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“…Recent studies by Li et al and Zhang et al performed a comprehensive safety evaluation of a PAM imaging system used to visualize retinal blood vessels and showed that pulsed-laser energy levels at 1.6 nJ (1 % of the ANSI safety limit) were able to generate defined images of the retinal vasculature without damage as per histological analysis [ 88 , 89 ], demonstrating that ultralow energy PAM systems can likely be applied safely in the future in clinical eye settings. In addition to uses in ophthalmology, PAM can be used for a variety of imaging applications, including oncology [ 90 , 91 ], neurology [ 92 , 93 ], dermatology [ 94 ], and gastroenterology [ 95 ]. While still a new and ongoing development, PAM imaging shows promise as an ophthalmic modality capable of safely producing images of high resolution and penetrance for the diagnosis and tracking of a variety of eye conditions.…”

Section: Advanced Ophthalmic Imagingmentioning

confidence: 99%

Advanced nanomaterials for imaging of eye diseases

Nguyen,

Hu,

Zhe

et al. 2024

ADMET DMPK

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Background and purpose: Vision impairment and blindness present significant global challenges, with common causes including age-related macular degeneration, diabetes, retinitis pigmentosa, and glaucoma. Advanced imaging tools, such as optical coherence tomography, fundus photography, photoacoustic microscopy, and fluorescence imaging, play a crucial role in improving therapeutic interventions and diagnostic methods. Contrast agents are often employed with these tools to enhance image clarity and signal detection. This review aims to explore the commonly used contrast agents in ocular disease imaging. Experimental approach: The first section of the review delves into advanced ophthalmic imaging techniques, outlining their importance in addressing vision-related issues. The emphasis is on the efficacy of therapeutic interventions and diagnostic methods, establishing a foundation for the subsequent exploration of contrast agents. Key results: This review focuses on the role of contrast agents, with a specific emphasis on gold nanoparticles, particularly gold nanorods. The discussion highlights how these contrast agents optimize imaging in ocular disease diagnosis and monitoring, emphasizing their unique properties that enhance signal detection and imaging precision. Conclusion: The final section, we explores both organic and inorganic contrast agents and their applications in specific conditions such as choroidal neovascularization, retinal neovascularization, and stem cell tracking. The review concludes by addressing the limitations of current contrast agent usage and discussing potential future clinical applications. This comprehensive exploration contributes to advancing our understanding of contrast agents in ocular disease imaging and sets the stage for further research and development in the field.

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Section: Advanced Ophthalmic Imagingmentioning

confidence: 99%

Advanced nanomaterials for imaging of eye diseases

Nguyen,

Hu,

Zhe

et al. 2024

ADMET DMPK

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Full-optical photoacoustic imaging using speckle analysis and resolution enhancement by orthogonal pump patterns projection

Vorobev,

Weidmann,

Agdarov

et al. 2023

Sci Rep

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This paper presents an approach for achieving full optical photoacoustic imaging with enhanced resolution utilizing speckle pattern analysis. The proposed technique involves projecting patterns derived from binary masks corresponding to orthogonal functions onto the target to elicit a photoacoustic signal. The resulting signal is then recorded using a high-speed camera and analyzed using correlation analysis of the speckle motion. Our results demonstrate the feasibility of this optical approach to achieve imaging with enhanced resolution without the need for physical contact with the target, opening up new possibilities for non-invasive medical imaging and other applications.

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Applications of photoacoustic spectroscopy and imaging in gastroenterology

Cited by 2 publications

References 48 publications

Advanced nanomaterials for imaging of eye diseases

Advanced nanomaterials for imaging of eye diseases

Full-optical photoacoustic imaging using speckle analysis and resolution enhancement by orthogonal pump patterns projection

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