Applications of mass spectrometry in cosmetic analysis: An overview

Shang, Yuhan; Meng, Xianshuang; Liu, Juan; Song, Naining; Zheng, Hui; Han, Chao; Ma, Qiang

doi:10.1016/j.chroma.2023.464175

Cited by 5 publications

(3 citation statements)

References 147 publications

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“…This method is suitable for both organic and inorganic compounds containing chemical bonds, frequently used in the analysis of lipids, fragrances, and moisturizers in cosmetics [ 127 ]. Mass spectrometry (MS) identifies molecular mass and composition by measuring the trajectory of molecules in electric or magnetic fields, applicable to nearly all compounds and particularly suited for the qualitative and quantitative analyses of complex cosmetic components [ 128 ]. Nuclear magnetic resonance (NMR) leverages the absorption and emission of radio waves by atomic nuclei in an external magnetic field, applicable to organic compounds containing active nuclei (such as 1 H, 13 C), and is instrumental in analyzing the structure of complex organic compounds in cosmetics [ 129 ].…”

Section: Compositions and Representative Compounds Of Cosmeticsmentioning

confidence: 99%

Decoding Cosmetic Complexities: A Comprehensive Guide to Matrix Composition and Pretreatment Technology

Du,

He,

Chen

et al. 2024

Molecules

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Despite advancements in analytical technologies, the complex nature of cosmetic matrices, coupled with the presence of diverse and trace unauthorized additives, hinders the application of these technologies in cosmetics analysis. This not only impedes effective regulation of cosmetics but also leads to the continual infiltration of illegal products into the market, posing serious health risks to consumers. The establishment of cosmetic regulations is often based on extensive scientific experiments, resulting in a certain degree of latency. Therefore, timely advancement in laboratory research is crucial to ensure the timely update and adaptability of regulations. A comprehensive understanding of the composition of cosmetic matrices and their pretreatment technologies is vital for enhancing the efficiency and accuracy of cosmetic detection. Drawing upon the China National Medical Products Administration’s 2021 Cosmetic Classification Rules and Classification Catalogue, we streamline the wide array of cosmetics into four principal categories based on the following compositions: emulsified, liquid, powdered, and wax-based cosmetics. In this review, the characteristics, compositional elements, and physicochemical properties inherent to each category, as well as an extensive overview of the evolution of pretreatment methods for different categories, will be explored. Our objective is to provide a clear and comprehensive guide, equipping researchers with profound insights into the core compositions and pretreatment methods of cosmetics, which will in turn advance cosmetic analysis and improve detection and regulatory approaches in the industry.

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Section: Compositions and Representative Compounds Of Cosmeticsmentioning

confidence: 99%

Decoding Cosmetic Complexities: A Comprehensive Guide to Matrix Composition and Pretreatment Technology

Du,

He,

Chen

et al. 2024

Molecules

View full text Add to dashboard Cite

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“…Validating a method to identify and quantify the suspected allergens (24) limited by EU regulations in fragrances by GC×GC-qMS.…”

Section: Gc×gc Qms (Sim Mode)mentioning

confidence: 99%

“…The analysis of cosmetics represents a challenge mainly because of the great variety of ingredients and formulations leading to immense matrix complexity and variability. In this field, many analytical techniques play a crucial role, each designed to meet specific demands to understand the molecular nature of cosmetic products and the complexity of their formulations: chromatography (liquid chromatography (LC) [ 5 , 6 ], gas chromatography (GC) [ 7 , 8 ], supercritical fluid chromatography (SFC) [ 9 ], capillary electrophoresis (CE) [ 10 , 11 ], spectroscopy [ 12 , 13 , 14 , 15 , 16 , 17 ], electrochemistry [ 18 ], colorimetry [ 19 , 20 ], mass spectrometry (MS) [ 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 ], interfacial methods [ 32 , 33 ], rheological assessment [ 34 , 35 , 36 ], olfactometry, and electronic nose technology [ 37 , 38 , 39 ]. Recent advances in MS and ionization techniques provide access to richer and deeper information on monitoring the molecular compositions of endogenous or exogenous compounds in or on the skin as well as those used in cosmetic formulations, with less time and effort.…”

Section: Introductionmentioning

confidence: 99%

Mass-Spectrometry-Based Research of Cosmetic Ingredients

Serb,

Georgescu,

Onulov

et al. 2024

Molecules

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Cosmetic products are chemical substances or mixtures used on the skin, hair, nails, teeth, and the mucous membranes of the oral cavity, whose use is intended to clean, protect, correct body odor, perfume, keep in good condition, or change appearance. The analysis of cosmetic ingredients is often challenging because of their huge complexity and their adulteration. Among various analytical tools, mass spectrometry (MS) has been largely used for compound detection, ingredient screening, quality control, detection of product authenticity, and health risk evaluation. This work is focused on the MS applications in detecting and quantification of some common cosmetic ingredients, i.e., preservatives, dyes, heavy metals, allergens, and bioconjugates in various matrices (leave-on or rinse-off cosmetic products). As a global view, MS-based analysis of bioconjugates is a narrow field, and LC- and GC/GC×GC-MS are widely used for the investigation of preservatives, dyes, and fragrances, while inductively coupled plasma (ICP)-MS is ideal for comprehensive analysis of heavy metals. Ambient ionization approaches and advanced separation methods (i.e., convergence chromatography (UPC2)) coupled to MS have been proven to be an excellent choice for the analysis of scented allergens. At the same time, the current paper explores the challenges of MS-based analysis for cosmetic safety studies.

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