Applications of laser technology in the manipulation of human spermatozoa

Xue, Yamei; Xiong, Yuping; Cheng, Xiaohong; Li, Kun

doi:10.1186/s12958-023-01148-9

Cited by 5 publications

(1 citation statement)

References 107 publications

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“…With the development of assisted reproductive techniques (ART), the use of laser technology in intracytoplasmic sperm injection (ICSI), preimplantation genetic testing (PGT), and in vitro manipulation of gametes and embryos has seen significant advancements over the past few decades [ 1 ]. Numerous studies have been conducted to explore the application of various laser technologies in the in vitro manipulation of human sperm, which involves sperm selection, sorting, immobilization, and quality assessment [ 1 , 2 ]. However, despite the extensive application of laser in ART, fewer studies focused on the effect of laser on human spermatozoa.…”

Section: Introductionmentioning

confidence: 99%

Time and power dependence of laser-induced photodamage on human sperm revealed by longitudinal rolling measurement using optical tweezers

He,

Wei,

Wang

et al. 2024

Biomed. Opt. Express

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Lasers are widely applied in assisted reproductive technologies, including sperm fixation, sperm selection and intracytoplasmic sperm injections, to reduce procedure time and improve consistency and reproducibility. However, quantitative studies on laser-induced photodamage of sperm are lacking. In this study, we demonstrated that, by using optical tweezers, the kinematic parameters of freely swimming sperm are correlated with the frequency as well as the percentage of pausing duration of longitudinal rolling of the same sperm head in the optical trap. Furthermore, by trapping individual sperm cells using 1064-nm optical tweezers, we quantitatively characterized the time-dependence of longitudinal rolling frequency and percentage of pausing duration of sperm under different laser powers. Our study revealed that, as trapping time and the laser power time increase, the longitudinal rolling frequency of the optically trapped sperm decreases with an increasing percentage of pausing duration, which characterizes the effect of laser power and duration on the photodamage of individual sperm cells. Our study provides experimental basis for the optimization of laser application in assisted reproductive technology, which may reduce the photodamage-induced biosafety risk in the future.

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Section: Introductionmentioning

confidence: 99%

Time and power dependence of laser-induced photodamage on human sperm revealed by longitudinal rolling measurement using optical tweezers

He,

Wei,

Wang

et al. 2024

Biomed. Opt. Express

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Configurable lateral optical forces from twisted mixed-dimensional MoO₃ homostructures

Yan,

Chen,

et al. 2024

J. Opt.

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In recent years, the concept of hyperbolic phonon polaritons (HPPs) has revolutionized the field of nanophotonic, enabling unprecedented control over light-matter interactions at the nanoscale. Here, we theoretically propose and study the lateral optical forces in twisted mixed-dimensional MoO3 homostructures. Assisted with the low-symmetry hyperbolic phonon polaritons, we realized a lateral optical force exerted on the Au nanoparticle near the surface of mixed-dimensional MoO3 homostructures with a linear polarized incident light. By controlling the polarization state, incident angle of light and the twisted angle of MoO3, the amplitude and direction of the lateral optical forces can be tailored in the mid-infrared range. Our findings provide a new platform for engineering lateral optical forces to manipulate diverse objects in a flexible and efficient manner.

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The effects of photobiomodulation on the improvement of sperm parameters: A review study

Parvin,

Erabi,

Saboohi Tasooji

et al. 2024

Photochem & Photobiology

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The prevalence of male infertility has become a significant clinical concern worldwide, with a noticeable upward trend in recent times. The rates of fertilization and subsequent development of embryos are dependent on many parameters associated with the quality and viability of sperm. Photobiomodulation (PBM) is a promising approach with a great potential for translational applications in the treatment of spermatozoa exhibiting low quality and motility. In this study, a comprehensive analysis of the existing literature, specifically examining the mechanisms of action of PBM has been presented. Our objective was to enhance knowledge in the field of laser light therapy in order to promote the usage of irradiation in clinical settings in a more effective way. Within the realm of reproductive science, the utilization of PBM has been employed to enhance the metabolic processes, motility, and viability of spermatozoa. This is attributed to its advantageous effects on mitochondria, resulting in the activation of the mitochondrial respiratory chain and subsequent synthesis of ATP. This therapeutic approach can be highly advantageous in circumventing the reliance on chemical substances within the culture medium for spermatozoa while also facilitating the viability and motility of spermatozoa, particularly in circumstances involving thawing or samples with significant immotility.

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Applications of laser technology in the manipulation of human spermatozoa

Cited by 5 publications

References 107 publications

Time and power dependence of laser-induced photodamage on human sperm revealed by longitudinal rolling measurement using optical tweezers

Time and power dependence of laser-induced photodamage on human sperm revealed by longitudinal rolling measurement using optical tweezers

Configurable lateral optical forces from twisted mixed-dimensional MoO₃ homostructures

The effects of photobiomodulation on the improvement of sperm parameters: A review study

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Applications of laser technology in the manipulation of human spermatozoa

Cited by 5 publications

References 107 publications

Time and power dependence of laser-induced photodamage on human sperm revealed by longitudinal rolling measurement using optical tweezers

Time and power dependence of laser-induced photodamage on human sperm revealed by longitudinal rolling measurement using optical tweezers

Configurable lateral optical forces from twisted mixed-dimensional MoO3 homostructures

The effects of photobiomodulation on the improvement of sperm parameters: A review study

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Product

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Configurable lateral optical forces from twisted mixed-dimensional MoO₃ homostructures