Applications of ICP‐MS in Human Biomonitoring Studies

Heitland, Peter; Köster, Helmut D.

doi:10.1002/9781118271858.ch13

Cited by 6 publications

(4 citation statements)

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“…Current analytical techniques for the screening and detection of mercuric ion including atomic absorption spectroscopy, − inductively coupled plasma mass spectroscopy, − and selective cold vapor atomic (CV) absorption/fluorescence spectrometry (AAS/AFS) − are somewhat expensive and time-consuming. Several effective sensor systems for detection of Hg 2+ based on organic fluorophores or chromophores − have been developed.…”

Section: Introductionmentioning

confidence: 99%

Directed Self-Assembly of C₄-Symmetric, Oxidovanadate-Centered, Vanadyl(V) Quadruplexes for Ba²⁺- and Hg²⁺-Specific Recognition, Transport, and Recovery

et al. 2018

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Directed assembly of loosely, Na-bound, oxidovanadate-centered quartets of C-symmetry from tailor-made chiral N-salicylidene-vanadyl(V) complexes, for the first time, allows for highly efficient Ba- or Hg-specific detection (by V NMR and VCD), transport (forming a unique helical capsule or a capped square planar complex, respectively), and green recovery from an aqueous phase containing 4 different alkaline earth ions or from at least 10 different metal ions of similar size and charge capacity into the CHCl layer without interference from oxa- or oxophilic ions like Mg, Ca, Cu, Cd, and Pb.

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Section: Introductionmentioning

confidence: 99%

Directed Self-Assembly of C₄-Symmetric, Oxidovanadate-Centered, Vanadyl(V) Quadruplexes for Ba²⁺- and Hg²⁺-Specific Recognition, Transport, and Recovery

et al. 2018

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“…If the earlier studies mainly used different (AAS) techniques for heavy metal detection in blood and plasma, recently the Inductively Coupled Plasma Mass Spectrometry (ICP-MS) and Inductively Coupled Plasma-Optical Emission Spectrometry (ICP-OES) have been preferred due to much lower detection limits (46). ICP-MS and ICP-OES have been applied in several studies of populations living near industrially contaminated sites (47-49).…”

Section: Chemical Analysis Of Biomarkersmentioning

confidence: 99%

Human Biomonitoring in the Oil Shale Industry Area in Estonia—Overview of Earlier Programmes and Future Perspectives

Orru

Viitak

Herodes

et al. 2020

Front. Public Health

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“…Different analytical techniques exist to estimate the levels of toxic and trace elements in whole blood samples, including, Graphite Furnace Atomic Absorption Spectrometry (GFAAS), anodic stripping voltammetry (ASV), inductively coupled plasma with atomic emission spectrometry (ICP-AES), and inductively coupled plasma mass spectrometry (ICPMS) (WHO, 2020). However, ICPMS is considered the most pro cient technique for conducting extensive biomonitoring surveys due to its high sensitivity and robustness in determining a wide range of elements (Heitland & Köster, 2012).…”

Section: Introductionmentioning

confidence: 99%

Development and validation of an ICPMS method and its application in assessing heavy metals in whole blood samples among occupationally exposed Lead smelting plant workers

Upadhyay

2024

Preprint

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Occupational exposure to heavy metals affecting various organ systems, poses a significant health risk to workers. Consequently, its precise estimation is of clinical concern and warrants the need for an analytical method with reliable precision and accuracy. Current study aimed to develop an analytical method using inductively coupled plasma mass spectrometry (ICPMS) to detect trace to elevated levels of potentially toxic elements in human blood. The sample preparation optimized using a two-step ramp temperature microwave acid digestion program. The toxic elements quantified using ICPMS operating in kinetic energy dispersion (KED) mode, adjusting data acquisition parameters and instrumental settings. The analytical method was validated using standard performance parameters. Each validation parameter aligned with the acceptable criteria outlined in standard guidelines. The method achieved optimal linearity (r2 > 0.99), recovery (85.60–112.00%), precision (1.35–7.03%), capable of detecting the lowest concentration of 0.32, 0.28, 0.28, and 0.19 µg/L, and quantifying trace levels of 1.01, 0.88, 0.90, and 0.62 µg/L for arsenic (As), cadmium (Cd), mercury (Hg), and lead (Pb), respectively. Post-validation, the method was applied to estimate heavy metals in blood samples from 250 Pb smelting plant workers, revealing potential health implications of occupational exposure. The cohort analysis revealed demographic and employment factors were associated with elevated blood lead levels (BLL), leading to symptoms and health risks. Clinical analysis indicated 33.6% participants experienced hypertension, and 20 were anemic at BLL above 300 µg/L. It emphasizes the importance of continuous monitoring, interventions, and improved occupational hygiene to protect the well-being of workers.

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Applications of ICP‐MS in Human Biomonitoring Studies

Cited by 6 publications

References 113 publications

Directed Self-Assembly of C₄-Symmetric, Oxidovanadate-Centered, Vanadyl(V) Quadruplexes for Ba²⁺- and Hg²⁺-Specific Recognition, Transport, and Recovery

Directed Self-Assembly of C₄-Symmetric, Oxidovanadate-Centered, Vanadyl(V) Quadruplexes for Ba²⁺- and Hg²⁺-Specific Recognition, Transport, and Recovery

Human Biomonitoring in the Oil Shale Industry Area in Estonia—Overview of Earlier Programmes and Future Perspectives

Development and validation of an ICPMS method and its application in assessing heavy metals in whole blood samples among occupationally exposed Lead smelting plant workers

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Applications of ICP‐MS in Human Biomonitoring Studies

Cited by 6 publications

References 113 publications

Directed Self-Assembly of C4-Symmetric, Oxidovanadate-Centered, Vanadyl(V) Quadruplexes for Ba2+- and Hg2+-Specific Recognition, Transport, and Recovery

Directed Self-Assembly of C4-Symmetric, Oxidovanadate-Centered, Vanadyl(V) Quadruplexes for Ba2+- and Hg2+-Specific Recognition, Transport, and Recovery

Human Biomonitoring in the Oil Shale Industry Area in Estonia—Overview of Earlier Programmes and Future Perspectives

Development and validation of an ICPMS method and its application in assessing heavy metals in whole blood samples among occupationally exposed Lead smelting plant workers

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Product

Resources

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Directed Self-Assembly of C₄-Symmetric, Oxidovanadate-Centered, Vanadyl(V) Quadruplexes for Ba²⁺- and Hg²⁺-Specific Recognition, Transport, and Recovery

Directed Self-Assembly of C₄-Symmetric, Oxidovanadate-Centered, Vanadyl(V) Quadruplexes for Ba²⁺- and Hg²⁺-Specific Recognition, Transport, and Recovery