Applications of High Performance Liquid Chromatography in the Analysis of Herbal Products

Sarker, Satyajit D.; Nahar, Lutfun

doi:10.1016/b978-0-12-800874-4.00019-2

Cited by 22 publications

(56 citation statements)

References 63 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Other than its accuracy, PCA can visualise the cluster of the samples on a score plot and reduce the time spent on discrimination. This statement is supported by a previous study by Sarker and Nahar [31]. With advanced computational techniques, PCA has become a rapid tool for analysing the enormous data obtained and shortens the analysis time [32].…”

Section: Discrimination Of Herbal Products From the Zingiberaceae Fam...supporting

confidence: 65%

Discrimination of Herbal Products from Zingiberaceae Family Using Electric Nose Combined with Chemometric Techniques

2021

MJCHEM

View full text Add to dashboard Cite

Many herbs from the Zingiberaceae family are widely used as raw materials in herbal products. Some of them have a similar colour for their rhizomes and are quite hard to distinguish from each other, so it is possible to misidentify one for the other. Therefore, it is necessary to find a rapid and reliable method for discrimination of Zingiberaceae-based products. The present work investigates the possibility of applying electric nose (e-nose) combined with chemometric techniques for discrimination of herbal products from the Zingiberaceae family. Nine powdered samples consisting of Alpinia galanga, Alpinia conchigera, Curcuma longa, Curcuma zedoaria, Curcuma xanthorrhiza, Zingiber officinale, Zingiber zerumbet, Kaempferia galangal, and Kaempferia pandurata were analysed by using e-nose. As a result, e-nose identified several volatile compounds for each sample. Next, the responses from e-nose were used for principal component analysis (PCA) and discriminant function analysis (DFA) to visualise the dataset using score plots. The result demonstrates that the combination of e-nose and PCA and DFA could discriminate the samples, in which DFA gave clearer discrimination between all samples. This combination can be used for rapid discrimination of Zingiberaceae-based products, which could contribute to the quality control in the herbal industry's supply chain.

show abstract

Section: Discrimination Of Herbal Products From the Zingiberaceae Fam...supporting

confidence: 65%

Discrimination of Herbal Products from Zingiberaceae Family Using Electric Nose Combined with Chemometric Techniques

2021

MJCHEM

View full text Add to dashboard Cite

show abstract

“…High-performance liquid chromatography ( HPLC) is a modern, robust, and popularly used separation method, which is also used for identification, quantification and fingerprinting of compounds from a crude mixture [ 92 ].…”

Section: Identification Characterization and Quantification Of The Bioactive Compounds From Seaweeds Extractsmentioning

confidence: 99%

Marine Health-Promoting Compounds: Recent Trends for Their Characterization and Human Applications

Quitério

Soares

Ferraz

et al. 2021

Foods

View full text Add to dashboard Cite

Seaweeds represent a rich source of biologically active compounds with several applications, especially in the food, cosmetics, and medical fields. The beneficial effects of marine compounds on health have been increasingly explored, making them an excellent choice for the design of functional foods. When studying marine compounds, several aspects must be considered: extraction, identification and quantification methods, purification steps, and processes to increase their stability. Advanced green techniques have been used to extract these valuable compounds, and chromatographic methods have been developed to identify and quantify them. However, apart from the beneficial effects of seaweeds for human health, these natural sources of bioactive compounds can also accumulate undesirable toxic elements with potential health risks. Applying purification techniques of extracts from seaweeds may mitigate the amount of excessive toxic components, ensuring healthy and safer products for commercialization. Furthermore, limitations such as stability and bioavailability problems, chemical degradation reactions during storage, and sensitivity to oxidation and photo-oxidation, need to be overcome using, for example, nanoencapsulation techniques. Here we summarize recent advances in all steps of marine products identification and purification and highlight selected human applications, including food and feed applications, cosmetic, human health, and fertilizers, among others.

show abstract

“…High‐performance liquid chromatography or high‐pressure liquid chromatography (HPLC), is one of the most popular, modern, powerful and versatile chromatographic separation techniques that have been routinely used to separate, identify and quantify components from complex mixtures, e.g. an herbal extracts or products, and to obtain chemical profiles or fingerprints of crude mixtures. In a standard HPLC operation, a compact column is usually 2.0–4.6 mm in diameter, and 20–250 mm in length, packed with a stationary phase, e.g.…”

Section: Hplc and Uplc/uhplcmentioning

confidence: 99%

“…The use of tandem mass spectrometry (MS/MS), which provides fragments through collision‐induced dissociation of the molecular ions, has increased significantly in recent years . However, an HPLC‐MS or HPLC‐MS/MS system does not always allow a complete and unambiguous on‐line identification of any component, unless it is a well‐known compound, and complementary on‐line spectroscopic information is available in databases for comparison . The quality of MS response invariably depends on a number of factors, e.g.…”

Section: Hplc and Uplc/uhplcmentioning

confidence: 99%

A review on the recent advances in HPLC, UHPLC and UPLC analyses of naturally occurring cannabinoids (2010–2019)

Nahar

Önder

Sarker

2019

Phytochemical Analysis

Self Cite

View full text Add to dashboard Cite

Introduction Organic molecules that bind to cannabinoid receptors are called cannabinoids, and they have similar pharmacological properties like the plant, Cannabis sativa L. Hyphenated liquid chromatography (LC), incorporating high‐performance liquid chromatography (HPLC) and ultra‐performance liquid chromatography (UPLC, also known as ultrahigh‐performance liquid chromatography, UHPLC), usually coupled to an ultraviolet (UV), UV‐photodiode array (PDA) or mass spectrometry (MS) detector, has become a popular analytical tool for the analysis of naturally occurring cannabinoids in various matrices. Objective To review literature on the use of various LC‐based analytical methods for the analysis of naturally occurring cannabinoids published since 2010. Methodology A comprehensive literature search was performed utilising several databases, like Web of Knowledge, PubMed and Google Scholar, and other relevant published materials including published books. The keywords used, in various combinations, with cannabinoids being present in all combinations, in the search were Cannabis, hemp, cannabinoids, Cannabis sativa, marijuana, analysis, HPLC, UHPLC, UPLC, quantitative, qualitative and quality control. Results Since 2010, several LC methods for the analysis of naturally occurring cannabinoids have been reported. While simple HPLC‐UV or HPLC‐UV‐PDA‐based methods were common in cannabinoids analysis, HPLC‐MS, HPLC‐MS/MS, UPLC (or UHPLC)‐UV‐PDA, UPLC (or UHPLC)‐MS and UPLC (or UHPLC)‐MS/MS, were also used frequently. Applications of mathematical and computational models for optimisation of different protocols were observed, and pre‐analyses included various environmentally friendly extraction protocols. Conclusions LC‐based analysis of naturally occurring cannabinoids has dominated the cannabinoids analysis during the last 10 years, and UPLC and UHPLC methods have been shown to be superior to conventional HPLC methods.

show abstract

Applications of High Performance Liquid Chromatography in the Analysis of Herbal Products

Cited by 22 publications

References 63 publications

Discrimination of Herbal Products from Zingiberaceae Family Using Electric Nose Combined with Chemometric Techniques

Discrimination of Herbal Products from Zingiberaceae Family Using Electric Nose Combined with Chemometric Techniques

Marine Health-Promoting Compounds: Recent Trends for Their Characterization and Human Applications

A review on the recent advances in HPLC, UHPLC and UPLC analyses of naturally occurring cannabinoids (2010–2019)

Contact Info

Product

Resources

About