Applications of Fungi Secondary Metabolites in the Food Industry

Moura, Marília Aparecida Fidelis e; Gomes, Dhionne Corrêia; Takahashi, Jacqueline Aparecida

doi:10.1007/978-3-031-18587-8_24

Cited by 2 publications

(1 citation statement)

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“…and Aspergillus terreus. Also, other aspergillus species, such as Eurotium cristatum, Aspergillus niger, Aspergillus terreus, Aspergillus flavus, etc., can produce lovastatin [31,32]. However, the yield of lovastatin in Eurotium cristatum is very low [33][34][35][36].…”

Section: Introductionmentioning

confidence: 99%

High-Value Utilization of Tea Forest Resources: Breeding Eurotium cristatum Strains to Enhance Lovastatin Yields in Anhua Dark Tea

Li,

Liu,

Liu

et al. 2023

Forests

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The tea plant is a vital strategic forest resource in China. Dark tea produced from its leaves is an indispensable health-promoting product in western China due to its unique lipid-lowering function. Eurotium cristatum is the dominant strain in Fuzhuan brick tea (a variety of Anhua dark tea) and could produce many functional components, including lovastatin, a lipid-lowering compound. In this study, the lovastatin yield of dark tea was improved by breeding Eurotium cristatum using the protoplast fusion method. The experiments were carried out by inducing a fusion between inactivated Eurotium cristatum JH1205 and Monascus CICC5031. Among the 92 fusants screened the HPLC method, four strains (A4, A36, A54, and A76) with higher lovastatin production (more than three times as high) were obtained. The A76 strain had the highest lovastatin yield, which was 23.93 μg/mL. The location of the tea forest strongly influenced the lovastatin yield of loose dark tea. The strain bred in this study improved the lovastatin yield of loose dark tea by more than three times when compared to wild Eurotium cristatum. These results are promising for the development of tea forest resources.

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