Applications of Chemically Modified Carbon Nanotubes for Tissue Engineering

Esmaeili, Yasaman; Mirahmadi‐Zare, Seyede Z.; Bigham, Ashkan; Boshtam, Maryam; Gharghish, Saba; Zomorrodi, Raha

doi:10.1002/9783527838790.ch16

Cited by 2 publications

(2 citation statements)

References 99 publications

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“…33 It has been established that adding polar functional groups such as COOH to the surface of CNTs significantly decreases the toxic effects of the CNTs. 34 When CNTs come into direct contact with microorganisms, they can damage their cell membranes and kill them. Because of their high surface-to-volume ratio and enormous interior volume, CNTs have been attributed to bacteriostatic qualities.…”

Section: Introductionmentioning

confidence: 99%

“…Due to their antibacterial activity, reasonably high biocompatibility, ability to stimulate angiogenesis, and excellent physical and chemical characteristics, carbon nanotubes (CNTs) and decorated CNTs have lately gained much interest as additives in biopolymers for the production of innovative composite biomaterials . It has been established that adding polar functional groups such as COOH to the surface of CNTs significantly decreases the toxic effects of the CNTs . When CNTs come into direct contact with microorganisms, they can damage their cell membranes and kill them.…”

Section: Introductionmentioning

confidence: 99%

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Drug-Loaded Carbon Nanotube Incorporated in Nanofibers: A Multifunctional Nanocomposite for Smart Chronic Wound Healing

Shakiba

Jahangiri

Rahmani

et al. 2023

ACS Appl. Polym. Mater.

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A proper dressing for chronic wounds should be able to preserve moisture while absorbing the exudates and exhibit good antibacterial properties and reliable mechanical properties. Furthermore, drug delivery through a wound dressing is an added value that brings more therapeutic and regenerative functionalities. In this study, a carboxylated multiwalled carbon nanotube–curcumin hybrid composite was embedded in a polyamide 6/poly(vinyl alcohol) nanofibrous composite (PA6/PVA/CMWCNT-Cur) for controlled drug release and potential wound healing application. PA6/PVA/CMWCNT-Cur nanofibrous composites were synthesized in two steps. First, Cur was loaded throughout the CMWCNT, and then a cross-linked PA6/PVA/CMWCNT-Cur blend solution was electrospun at CMWCNT-Cur concentrations of 0.5, 0.75, and 1 wt %. The results showed that incorporating PVA and CMWCNT-Cur into the PA6 nanofiber improved its wettability, physical properties, and biodegradability. In addition, the optical density technique demonstrated that the produced nanofibers had high antibacterial activity, which effectively inhibited the development of Staphylococcus aureus and Escherichia coli bacteria. Due to its uniform nanofibrous structure, superior mechanical capabilities, and excellent antibacterial features, the PA6/PVA/CMWCNT-Cur hybrid nanofibrous composite containing 0.75 wt % CMWCNT-Cur was chosen as the most suitable sample. Studies on the release of Cur from the nanofibers at different pH values demonstrated a faster rate in mild acidic media. The cell viability against the L929 cell line showed that the PA6/PVA/CMWCNT-Cur hybrid nanofibrous composite significantly increased the cell viability and proliferation. This work provides a simple and quick strategy for producing a multifunctional nanofibrous mat for wound healing applications.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Drug-Loaded Carbon Nanotube Incorporated in Nanofibers: A Multifunctional Nanocomposite for Smart Chronic Wound Healing

Shakiba

Jahangiri

Rahmani

et al. 2023

ACS Appl. Polym. Mater.

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Study of properties of cements and concrete mixtures with carbon nanotubes

Kozlova,

Zemskova,

Skopova

et al. 2023

E3S Web Conf.

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The development of nanotechnology contributes to the production of a new generation of multifunctional building materials. Carbon nanotubes (CNTs) are one of the components that make it possible to obtain such materials. CNTs are so small that they are prone to aggregation. To exclude this phenomenon, it is necessary to subject the particles to ultrasonic dispersion and stabilization. The purpose of the study was determined, which is to stabilize CNT suspensions and study of the properties of cements and concrete mixtures containing stabilized CNT particles in their composition. During the research, we have established the optimal dispersion parameters (t = 25±2 °C, υ = 44 kHz, τ<30 min) and the stabilizer concentration (5 g/l). The tests on the compressive strength of modified cement samples showed that the complex additive, which includes polycarboxylates and CNTs, gives the maximum increase in strength in the first day by 60%, in 28 days - by 20%. The introduction of CNTs into the composition of the concrete mix increased the compressive strength by 32% on the 3rd day of hardening, and by 34-39% on the 28th day compared to the control composition without additives.

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Applications of Chemically Modified Carbon Nanotubes for Tissue Engineering

Cited by 2 publications

References 99 publications

Drug-Loaded Carbon Nanotube Incorporated in Nanofibers: A Multifunctional Nanocomposite for Smart Chronic Wound Healing

Drug-Loaded Carbon Nanotube Incorporated in Nanofibers: A Multifunctional Nanocomposite for Smart Chronic Wound Healing

Study of properties of cements and concrete mixtures with carbon nanotubes

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