Steel tubular profiles have outstanding mechanical and architectural performances, but their joints must be manufactured with a vast number of welds and local stiffeners, resulting in complex fabrication and low structural reliability under extreme loads. Fatigue failure is usually a dominant parameter in their design. On the other hand, nature perfectly optimizes its structures with minimized stress concentrations resulting in an extensive fatigue life. In the case of tubular structures, the nodes between the bamboo body and branches are inspiring examples. This article discusses how smarter solutions can be achieved using inspiration from nature by setting the objective of topology optimization to enhance the structural integrity of welded tubular joints between 3‐D‐printed and conventional steel components. Rather than focusing on the “weight reduction,” it prioritizes the objectives of resistance, robustness, and durability. 3‐D metal printing technology, unleashed from the constraints of traditional manufacturing, can enable this structural customization, bringing substantial savings to tubular joint fabrication costs and material waste. To quantify the performance of such joints, the strain energy density method can be the right tool, thanks to its independence on mesh size. This paper provides a review of these subjects and presents brief results of a case study.