Applications and Technology of Electronic Nose for Clinical Diagnosis

Abstract

Rapid advances in sensor technologies have facilitated the development of high-performance electronic noses that can detect and discriminate volatile compounds in situ. The research and development of electronic noses has resulted in a new qualitative and semi-quantitative detection approach in the field of clinical diagnostics. Electronic noses have a clear potential to be a non-invasive, simple and rapid but above all accurate early diagnostic screening tool. This review collates existing knowledge of recent advances in electronic nose technologies and applications.

A Review of Technologies for Detection and Measurement of Adulterants in Cereals and Cereal Products

“…The data computing system generates a fingerprint for the interaction between the scent from the target sample and the response from the chemical sensors that is compared to standard reference signals (Chen et al, 2013;Jiang et al, 2014). This technique has been applied in several settings including medicine, manufacturing, product standardization, and food authentication (Arshak et al, 2004, Chen et al, 2013Lippolis et al, 2014).…”

Electronic-Nose Technology and its Application -A Systematic Survey

“…This process is based on placing the sample hermetically in a sealed vial and extracting the volatile components once the equilibrium is established between the matrix and the gaseous phase. Sample temperature, equilibration time, vial size, sample quantity are some parameters that have to be optimized for efficiency,sensitivity, quantitation and reproductibility [3,4,5].…”

“…The volatile component is extracted from the sample onto the fiber .The absorbed compounds are desorbed by heating and then introduced into the detection system. Parameters like nature of absorbent deposited on fiber, equilibration time, sample temperature and extraction duration are to be optimized [3,5].…”

“…Here in this method the volatile components are purged by a stream of inert gas and trapped onto an absorbent. The trapped molecule are desorbed by heating and is introduced into the detection system which will increase the sensitivity for analysis [3,5,6]. …”

“…An optical sensor consist of: light source, suitable optics directing the light to or from sensor, sensing material, photodetector for detecting the light signal comes from the sensor [5,17].…”