Applications and Advantages of Gold Nanoparticles as X-Ray Contrast Agent

Abstract

A new contrast agent in medical imaging discovered and developed since 10 years ago and it's under study until this moment because the classic contrast agents impose earnest limitations on medical imaging abilities such as the short imaging time, poor contrast X-ray images for obese patients (over weighted patients) and real side effects renal problems and toxicity problems. The new contrast agent is the Gold Nanoparticles (GNP) may overcome these restrictions due to its properties where the (GNP) bio distribution is higher than tri-iodobenzene compounds. also, bone /tissue interference is more clear and obvious than tri-iodobenzene compounds and in general nanoparticles clear the blood slowly than classic contrast agents which permit for longer imaging time and all of that leads to enhancing the X-ray diagnostic. Gold Nanoparticles were injected intraperitoneally into mice then images were taken by conventional X-RAY unit. Tumors were seen clearly.