Application progress of microfluidics-integrated biosensing platforms in the detection of foodborne pathogens

Fu, Xuran; Sun, Jiadi; Liang, Rong; Guo, Hongyan; Wang, Liping; Sun, Xiulan

doi:10.1016/j.tifs.2021.07.006

Cited by 48 publications

(11 citation statements)

References 108 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The integration of the microfluidic device with analytical techniques such as electrochemical, fluorescence, SERS, SPR, etc. to generate a quantitative, semi‐quantitative, or colorimetric signal which can be easily interpreted to determine the presence or absence of target analytes 141–145 …”

Section: Integrated Microfluidic‐based Poct Devicesmentioning

confidence: 99%

“…to generate a quantitative, semi-quantitative, or colorimetric signal which can be easily interpreted to determine the presence or absence of target analytes. [141][142][143][144][145] Microfluidics platform offer numerous advantage such as fully automation process which reduces the time-consuming manual procedure that enables the rapid detection of analytes. However, the portability, multiplex detection, low sample requirement, and disposable nature efficiently improve the performance of the device which can offer on-site detection and reduces the overall cost of the device.…”

Section: Integrated Microfluidic-based Poct Devicesmentioning

confidence: 99%

See 1 more Smart Citation

Internet‐of‐medical‐things integrated point‐of‐care biosensing devices for infectious diseases: Toward better preparedness for futuristic pandemics

Parihar

Yadav

Sadique

et al. 2023

Bioengineering & Transla Med

View full text Add to dashboard Cite

Microbial pathogens have threatened the world due to their pathogenicity and ability to spread in communities. The conventional laboratory‐based diagnostics of microbes such as bacteria and viruses need bulky expensive experimental instruments and skilled personnel which limits their usage in resource‐limited settings. The biosensors‐based point‐of‐care (POC) diagnostics have shown huge potential to detect microbial pathogens in a faster, cost‐effective, and user‐friendly manner. The use of various transducers such as electrochemical and optical along with microfluidic integrated biosensors further enhances the sensitivity and selectivity of detection. Additionally, microfluidic‐based biosensors offer the advantages of multiplexed detection of analyte and the ability to deal with nanoliters volume of fluid in an integrated portable platform. In the present review, we discussed the design and fabrication of POCT devices for the detection of microbial pathogens which include bacteria, viruses, fungi, and parasites. The electrochemical techniques and current advances in this field in terms of integrated electrochemical platforms that include mainly microfluidic‐ based approaches and smartphone and Internet‐of‐things (IoT) and Internet‐of‐Medical‐Things (IoMT) integrated systems have been highlighted. Further, the availability of commercial biosensors for the detection of microbial pathogens will be briefed. In the end, the challenges while fabrication of POC biosensors and expected future advances in the field of biosensing have been discussed. The integrated biosensor‐based platforms with the IoT/IoMT usually collect the data to track the community spread of infectious diseases which would be beneficial in terms of better preparedness for current and futuristic pandemics and is expected to prevent social and economic losses.

show abstract

Section: Integrated Microfluidic‐based Poct Devicesmentioning

confidence: 99%

Section: Integrated Microfluidic-based Poct Devicesmentioning

confidence: 99%

Internet‐of‐medical‐things integrated point‐of‐care biosensing devices for infectious diseases: Toward better preparedness for futuristic pandemics

Parihar

Yadav

Sadique

et al. 2023

Bioengineering & Transla Med

View full text Add to dashboard Cite

show abstract

“…Microfluidics provides a powerful tool for testing applications with its advantages of portability, miniaturization, automation, multi-channel sample testing, minimization of hazardous material handling, and cost savings ( Ragab and El-Kimary, 2021 ; Su et al, 2021 ; Tseng et al, 2021 ). In addition, all analytical processes, including sample preparation, reaction, separation, and detection are integrated into a microfluidic chip for field test applications ( Fu et al, 2021 ; Xie et al, 2021c ). Biosensors that use a variety of technologies combined with microfluidic chips to detect foodborne pathogens have been widely reported ( Ali et al, 2020 ; Kaya et al, 2021 ).…”

Section: Microfluidic Detection Technologymentioning

confidence: 99%

Research progress on detection techniques for point-of-care testing of foodborne pathogens

Zhao

Huang

et al. 2022

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

The global burden of foodborne disease is enormous and foodborne pathogens are the leading cause of human illnesses. The detection of foodborne pathogenic bacteria has become a research hotspot in recent years. Rapid detection methods based on immunoassay, molecular biology, microfluidic chip, metabolism, biosensor, and mass spectrometry have developed rapidly and become the main methods for the detection of foodborne pathogens. This study reviewed a variety of rapid detection methods in recent years. The research advances are introduced based on the above technical methods for the rapid detection of foodborne pathogenic bacteria. The study also discusses the limitations of existing methods and their advantages and future development direction, to form an overall understanding of the detection methods, and for point-of-care testing (POCT) applications to accurately and rapidly diagnose and control diseases.

show abstract

“…Therefore, in the face of sudden outbreaks of unknown pathogens, rapid and accurate screening and identification is the key to interrupting disease transmission and reducing health hazards. 5 Pathogen detection technology mainly includes antigen detection and nucleic acid detection. 6 Among them, antigen detection based on the lateral flow immunoassay is more popular because of its simple operation, convenience, and speed, but its disadvantage is that the sensitivity is poor, and it cannot accurately diagnose people with low pathogen loads such as early infection and asymptomatic infection.…”

Section: Introductionmentioning

confidence: 99%

An integrated microfluidic chip for nucleic acid extraction and continued cdPCR detection of pathogens

Huang

Gao

et al. 2023

Analyst

View full text Add to dashboard Cite

show abstract

Application progress of microfluidics-integrated biosensing platforms in the detection of foodborne pathogens

Cited by 48 publications

References 108 publications

Internet‐of‐medical‐things integrated point‐of‐care biosensing devices for infectious diseases: Toward better preparedness for futuristic pandemics

Internet‐of‐medical‐things integrated point‐of‐care biosensing devices for infectious diseases: Toward better preparedness for futuristic pandemics

Research progress on detection techniques for point-of-care testing of foodborne pathogens

An integrated microfluidic chip for nucleic acid extraction and continued cdPCR detection of pathogens

Contact Info

Product

Resources

About