Application of Traditional Japanese Drug Jidabokuippo in a Modern Society

Abstract

Background: Jidabokuippo (JDI) (治打撲一方) has been used in Japan to alleviate contusion-induced swelling and pain since medieval times.Method: This review investigated the effects of JDI on various symptoms in patients with trauma or static blood[TM1]. The PubMed and Igaku Chuo Zasshi databases were searched until 24 December 2021. We summarize the benefits of applying JDI to inflammatory conditions, including bruises.Results: JDI has been used to resolve blood [TM1] stasis, regulate qi in trauma patients, and treat inflammatory swelling and pain caused by rheumatoid arthritis and cellulitis. As the adverse event rate associated with JDI is low (1.3%), JDI is considered a safe drug.Conclusion: JDI can be used to resolve blood[TM1] stasis in trauma patients without adverse events associated with nonsteroidal anti-inflammatory drugs.

Makyoyokukanto use in patients with painful afflictions

“…The most frequent adverse event was digestive symptoms (6.1%), and 10 of the 457 patients had epigastric distress (2.2%). We have previously studied the safety of jidabokuippo [13,14]. The adverse event rate was reported to be 1.3%, resulting in a low adverse event rate compared with reports using other Kampo formulas.…”

Symptoms associated with hematoma caused by radial artery injury successfully treated with jidabokuippo

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Symptoms associated with hematoma caused by radial artery injury successfully treated with jidabokuippo Dear Editor Jidabokuippo (JDI) is a herbal mixture used in Japan to alleviate contusion-induced swelling and pain caused by bruises and sprains. It has also been applied to various traumas and cellulitis [1]. There have been a few reports of JDI being applied for bleeding and pain after venipuncture; however, there are few reports on the symptoms after arterial puncture [2,3].We encountered a case in which JDI was useful for subcutaneous hematoma, swelling, and pain due to catheterization-induced radial artery injury.

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The pain‐relieving effect of jidabokuippo in bear‐related trauma

“…JDI is a herbal blend commonly used in Japan to alleviate swelling and pain associated with contusions [2]. It is used to manage bruising, sprains, traumatic injuries, and vascular damage [3].…”

“…Thus, JDI includes herbs with antioxidant effects that may have synergistic antioxidant effects. The Glycyrrhiza root also inhibits prostaglandin production and exerts analgesic effects [2]. Rhubarb rhizomes exert sedative effects and can alleviate blood stasis [4].…”

“…Cnidium rhizomes, cinnamon bark, and clove floral buds regulate qi. In short, the pain-relieving effect of JDI may be due to multiple pharmacological effects such as antiinflammatory, antiedematous, antithrombotic, sedative, and spasmolytic actions, and through improving blood circulation [2]. Therefore, when NSAIDs alone are insufficient, JDI may be considered as an alternative.…”