A series of triorganophosphinegold(1) dithiocarbamate (R3PAuS2CNR'2) and xanthate (R3PAuS2COR')
complexes have been prepared and characterised spectroscopically. Based on crystallographic evidence, the
molecules feature linear gold(1) geometries defined by sulphur and phosphorus donors. The complexes, along
with a series of known anti-cancer agents, have been screened against a panel of seven human cancer cell
lines. Uniformly, the dithiocarbamate derivatives are more active than their xanthate counterparts, with the
most active complex being Et3PAu(S2CNEt2), and are more active than cisplatin in all cell lines screened but,
not as potent as taxol.