Application of the Multicenter Automatic Defibrillator Implantation Trial II Risk Score in a Nontrial Setting

Naksuk, Niyada; Akkaya, Mehmet; Adabag, Selçuk

doi:10.1016/j.amjcard.2013.04.019

Cited by 17 publications

(7 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…We found that the cost of individual syncope/collapse‐related hospitalizations has increased significantly between 2004 and 2013, even after adjusting for the inflation rates. This could be secondary to (1) an increase in the use of diagnostic testing, and/or (2) an increase in the cost of such testing, or (3) an increase in the cost of care related to the higher comorbidity burden . Patients with pre‐existing cardiac disease, in whom syncope/collapse could be particularly concerning, may require expensive diagnostic tests in the hospital.…”

Section: Discussionmentioning

confidence: 99%

Trends of hospitalizations for syncope/collapse in the United States from 2004 to 2013–An analysis of national inpatient sample

Anand

Benditt

Adkisson

et al. 2018

Cardiovasc electrophysiol

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Trends of hospitalizations for syncope/collapse in the United States from 2004 to 2013–An analysis of national inpatient sample

Anand

Benditt

Adkisson

et al. 2018

Cardiovasc electrophysiol

Self Cite

View full text Add to dashboard Cite

show abstract

“…After twenty months follow-up patients with atrial fibrillation had higher cumulative frequency of hospitalizations and mortality compared with patients in sinus rhythm, noting that the presence of atrial fibrillation was not in itself an independent predictor of increased mortality, but affected more frequent hospitalizations. Sub-analysis of the MADIT II study (13) identified risk factors which reduced the benefit of ICD in reducing SCD such as: advanced age (over 70 years of age), severe heart failure, presence of chronic renal failure, presence of atrial fibrillation and wider QRS complexes. In our trial risk profile did not differ significantly between patient groups (exept higher serum concentration of NT-proBNP in patients with permanent atrial fibrillation), which may explain the equally two-year survival in all patient groups.…”

Section: Discussionmentioning

confidence: 99%

Influence of Atrial Fibrillation on Two-Year Survival of Patients with Implanted Cardioverter Defibrillator

Ignjatovic

Đokić-Nikolić

Simović

et al. 2022

Serbian Journal of Experimental and Clinical Research

View full text Add to dashboard Cite

Implantable cardioverter defibrillators (ICD) effectively reduce risk of sudden cardiac death in both primary and secondary prevention, but only a small proportion of patients included in the clinical trials had atrial fibrillation. It is still unclear whether patients with atrial fibrillation have the same benefit from ICD implantation as patients in sinus rhythm. This is a clinical, prospective study which included 210 patients in the period 2014-2018. ICD was implanted in the Clinical Center Kragujevac and a two-year follow-up was performed. Patients were divided into 2 groups: a group in sinus rhythm and a group of patients with atrial fibrillation (paroxysmal, persistent and permanent). At the end of the two-year follow-up, there was no difference in survival between the compared groups. The total number of cardioverter defibrillator activations did not differ between the groups, but a significantly higher number of inappropriate cardioverter defibrillator activations was registered in the group with atrial fibrillation. In most patients who had inappropriate defibrillator activation during the two-year follow-up, appropriate defibrillator activation was also registered.

show abstract

“…In their study, Iwona et al [17] accepted all-cause mortality as an endpoint in a population similar to that of MADIT study, and they showed that in addition to MADIT-ICD scores, some clinical parameters were also significant in predicting long-term mortality in a group of patients who were implanted with ICD for primary prevention purpose. Recently, Naksuk et al [18] stated that in a more limited population that was similar to that of MADIT, MADIT scores were useful in predicting all-cause mortality; however, they suggested that this scoring did not have a predictive value for appropriate shock. Similarly, we also found that there was no association between appropriate shock and MADIT-ICD scores.…”

Section: Discussionmentioning

confidence: 99%

Relation of MADIT ICD Score with Long Term Cardiovascular Events in Patients with Implantable Cardioverter Defibrilator

Uslu

Doğan

Duman

et al. 2018

North Clin Istanbul

View full text Add to dashboard Cite

OBJECTIVE: To test the hypothesis that multicenter automatic defibrillator implantation trial (MADIT) - implantable cardioverter-defibrillator (ICD) scores predict replacement requirement and appropriate shock in a mixed population including both primary and secondary prevention and long-term adverse cardiovascular events. METHODS: The study has a retrospective design. Patients who were implanted with ICD in the cardiology clinic of Atatürk University Faculty of Medicine between 2000 and 2013 were included in the study. For this purpose, 1394 patients who were implanted with a device in our clinic were reviewed. Then, those who were implanted with permanent pacemaker (n=1005), cardiac resynchronization treatment (CRT) (n=45) and CRT-ICD (n=198) were excluded. RESULTS: A total of 146 patients (98 males, 67.1%) with a mean age of 61.1 (±14.8) years were recruited. The median follow-up time was 21.5 months (mean 30.6±25.9 months; minimum 4 months, and maximum 120 months). The median MADIT-ICD scores in the patients were 2. MADIT-ICD scores were categorized as low in 15.1%, intermediate in 57.5%, and high score in 27.4% of patients. Accordingly, MADIT-ICD scores (1.29 [1.00–1.68], p=0.050), hemoglobin (0.86 [0.75–0.99], p=0.047), and left ventricular ejection fraction (EF) (0.97 [0.94–0.99], p=0.023) were determined as independent predictors of major adverse cardiovascular events in the long-term follow-up of ICD-implanted population. CONCLUSION: In this study, we showed that there was an independent association of long-term adverse cardiovascular events with MADIT-ICD score, hemoglobin, and EF in patients implanted with ICD.

show abstract

Application of the Multicenter Automatic Defibrillator Implantation Trial II Risk Score in a Nontrial Setting

Cited by 17 publications

References 16 publications

Trends of hospitalizations for syncope/collapse in the United States from 2004 to 2013–An analysis of national inpatient sample

Trends of hospitalizations for syncope/collapse in the United States from 2004 to 2013–An analysis of national inpatient sample

Influence of Atrial Fibrillation on Two-Year Survival of Patients with Implanted Cardioverter Defibrillator

Relation of MADIT ICD Score with Long Term Cardiovascular Events in Patients with Implantable Cardioverter Defibrilator

Contact Info

Product

Resources

About