Application of the deuterium-oxide dose-to-mother technique to determine the exclusivity of breastfeeding in women in Kanye, Botswana

Motswagole, Boitumelo Stokie; Matenge, S T P; Mongwaketse, Tiyapo; Bogopa, Juda; Kobue-Lekalake, Rosemary; Mosetlha, K; Kwape, Lemogang

doi:10.1080/16070658.2015.11734547

Cited by 10 publications

(14 citation statements)

References 24 publications

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“…27 Over-reporting of the EBF was also shown among Botswana mothers when the two EBF determination techniques were compared. 28 On the other hand, reported EBF practice by Bangladeshi mothers of infants averaging 14.3 weeks old was comparable to the objective DO technique among. 29 Previous studies however did not focus on maternal HIV infection.…”

Section: Discussionmentioning

confidence: 91%

Exclusive Breastfeeding Is More Common Among HIV-Infected Than HIV-Uninfected Kenyan Mothers at 6 Weeks and 6 Months Postpartum

Oiye

Mwanda

Mary

et al. 2017

Breastfeeding Medicine

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Section: Discussionmentioning

confidence: 91%

Exclusive Breastfeeding Is More Common Among HIV-Infected Than HIV-Uninfected Kenyan Mothers at 6 Weeks and 6 Months Postpartum

Oiye

Mwanda

Mary

et al. 2017

Breastfeeding Medicine

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“…Although both saliva and urine have been sampled in studies to measure breast milk intake with the 2 H oxide dose-to-mother technique (6,(17)(18)(19) , it is not known how the type of body fluid affects the estimate for breast milk intake. Therefore, we aimed to quantify and compare estimates of breast milk intake with the 2 H oxide dose-to-mother technique when based on either saliva or urine samples among 2-to 4-month-old children.…”

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confidence: 99%

Comparing saliva and urine samples for measuring breast milk intake with the²H oxide dose-to-mother technique among children 2–4 months old

et al. 2019

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Saliva and urine are the two main body fluids sampled when breast milk intake is measured with the 2H oxide dose-to-mother technique. However, these two body fluids may generate different estimates of breast milk intake due to differences in isotope enrichment. Therefore, we aimed to assess how the estimated amount of breast milk intake differs when based on saliva and urine samples and to explore whether the total energy expenditure of the mothers is related to breast milk output. We used a convenience sample of thirteen pairs of mothers and babies aged 2–4 months, who were exclusively breastfed and apparently healthy. To assess breast milk intake, we administered doubly labelled water to the mothers and collected saliva samples from them, while simultaneously collecting both saliva and urine from their babies over a 14-d period. Isotope ratio MS was used to analyse the samples for 2H and 18O enrichments. Mean breast milk intake based on saliva samples was significantly higher than that based on urine samples (854·5 v. 812·8 g/d, P = 0·029). This can be attributed to slightly higher isotope enrichments in saliva and to a poorer model fit for urine samples as indicated by a higher square root of the mean square error (14·6 v. 10·4 mg/kg, P = 0·001). Maternal energy expenditure was not correlated with breast milk output. Our study suggests that saliva sampling generates slightly higher estimates of breast milk intake and is more precise as compared with urine and that maternal energy expenditure does not influence breast milk output.

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“…Therefore, Aarts et al (2000) suggested the recall period should include 24 hour period and since birth to avoid error found. Motswagole et al (2015) showed that all Botswana mothers reported practising exclusive breastfeeding by maternal recall method, however only 61.2% were actually exclusive breastfeeding using isotopic data of D 2 O at 3 months. A similar result was also shown by Samuel et al (2012) in India, in which 90% mothers was classified as exclusive breastfeeding using maternal recall method, when only 23% was exclusive breastfeeding using isotopic data of D 2 O.…”

Section: Resultsmentioning

confidence: 99%

Comparison of Breastfeeding Practice Using Deuterium Oxide Dose to Mother Technique with Maternal Recall Breastfeeding Practice Among Mothers in Klang Valley

Chong

Safii

Isa

et al. 2019

JSKM

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The assessment of exclusive breastfeeding is important to invest the efforts to promote and support breastfeeding practices. Hence this study was carried out to compare breastfeeding practices among mothers using deuterium dose to mother technique with maternal recall breastfeeding practice. A total of 30 mother-infant pairs from a university hospital and government health clinics in Klang Valley participated and completed the study. Mother-infant pairs were recruited into the study when infants were aged 3 months ± 1 week. Anthropometric measurements (height, weight, waist circumference for mother; length and weight for infant) were carried out. Socio-demographic questionnaire was self-administered while breastfeeding practices were interview administered using maternal recall breastfeeding practice questionnaire (MRBF). This was followed by baseline saliva collection of mother-infant pairs before dose and 6 days after mothers were given 30 ± 0.01 g of D 2 O. The post dose saliva sample of mother-infant pairs were collected 6 times at day 1,2,3,4,13 and 14.The results showed that majority of mothers (57%) were university graduates but majority were stay at home mothers. Meanwhile, mothers had BMI with mean 25 ± 4 kg/m 2. The results from MRBF questionnaire showed that all mothers were practicing exclusive breastfeeding and their infant never received any water sources other than their breast milk. However, the deuterium dose to mother technique revealed only 3% of mothers were actually practicing exclusive breastfeeding. From the isotopic data, the calculated mean intake of milk was 721 ± 243 g/day while the mean non-milk oral intake of 122 ± 22 g/ day. In contrast exclusive breastfeeding infants received only 10 g/day non milk oral intake, demonstrating exclusive breastfeeding practice of mothers. There were different breastfeeding practice reported from mother using deuterium oxide dose to mother technique with maternal recall breastfeeding practice.

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Application of the deuterium-oxide dose-to-mother technique to determine the exclusivity of breastfeeding in women in Kanye, Botswana

Cited by 10 publications

References 24 publications

Exclusive Breastfeeding Is More Common Among HIV-Infected Than HIV-Uninfected Kenyan Mothers at 6 Weeks and 6 Months Postpartum

Exclusive Breastfeeding Is More Common Among HIV-Infected Than HIV-Uninfected Kenyan Mothers at 6 Weeks and 6 Months Postpartum

Comparing saliva and urine samples for measuring breast milk intake with the²H oxide dose-to-mother technique among children 2–4 months old

Comparison of Breastfeeding Practice Using Deuterium Oxide Dose to Mother Technique with Maternal Recall Breastfeeding Practice Among Mothers in Klang Valley

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Application of the deuterium-oxide dose-to-mother technique to determine the exclusivity of breastfeeding in women in Kanye, Botswana

Cited by 10 publications

References 24 publications

Exclusive Breastfeeding Is More Common Among HIV-Infected Than HIV-Uninfected Kenyan Mothers at 6 Weeks and 6 Months Postpartum

Exclusive Breastfeeding Is More Common Among HIV-Infected Than HIV-Uninfected Kenyan Mothers at 6 Weeks and 6 Months Postpartum

Comparing saliva and urine samples for measuring breast milk intake with the2H oxide dose-to-mother technique among children 2–4 months old

Comparison of Breastfeeding Practice Using Deuterium Oxide Dose to Mother Technique with Maternal Recall Breastfeeding Practice Among Mothers in Klang Valley

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Comparing saliva and urine samples for measuring breast milk intake with the²H oxide dose-to-mother technique among children 2–4 months old