Application of the computer vision system for evaluation of pathomorphological images

Gargin, Vitaliy; Radutny, Radiy; Titova, Ganna; Bibik, Dmytro; Kirichenko, Aleksey; Bazhenov, Oleksii

doi:10.1109/elnano50318.2020.9088898

Cited by 42 publications

(13 citation statements)

References 17 publications

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“…SCT examination can help to determine not only the main morphological aspects of the bone structure, but also to measure its density. Maybe our study will help for the development of artificial intellect or other computed technologies [21][22][23][24][25] for the future studying of medical care workers or doctors [26] in different severity cases of pathological changes in paranasal sinuses or oral cavity [27][28][29], that allows accepting our results as useful in different field. Conclusions 1.…”

Section: Resultsmentioning

confidence: 99%

Anatomical Predictions of Development of Rhinosinusitis and Its Complications

Alekseeva

2020

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Background. The anatomical structure of the paranasal sinuses of a person predetermines the risk of development, diversity of presentation, possibility of complications and features of surgical treatment of rhinosinusitis. Objective: of our study was to determine the thickness and density of the walls of the maxillary and frontal sinuses, which are potentially dangerous in terms of the development of complications. Materials and methods: Our study involved 121 subjects without any ENT diseases, who underwent SCT examination due to the reasons that were not related to abnormalities of ENT organs. Thickness and density in the region of the lower (orbital) wall and posterior (cerebral) wall of the frontal sinus were calculated. Results and Discussion: The maximum density was characteristic of the lower wall of the frontal sinus under physiological conditions and appeared 107.96 ± 201.64 Hu, the minimum for the lower wall was -29.98 ± 208.54 Hu. The thickness of the bone tissue in the frontal sinus was 4.05 ± 2.04 mm. Conclusion: The minimum density and thickness of the lower and posterior walls of the frontal sinus and upper and lower walls of the maxillary sinus was established under physiological conditions. The density of the posterior wall was found to be 25.4% lower than the density of the lower wall, and the thickness 22.2% lower.

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Section: Resultsmentioning

confidence: 99%

Anatomical Predictions of Development of Rhinosinusitis and Its Complications

Alekseeva

2020

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“…Subsequently, staining with hematoxylin and eosin was performed. Microscopic examination was carried out on an Olympus BX41 microscope, followed by morphometric examination using the Olympus DP-soft 3.12 software [11].…”

Section: Methodsmentioning

confidence: 99%

Features of Endometrium Structure in Alcohol-Abusing Hiv-Infected Individuals

Lytvynenko

2021

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Background. Patients with comorbid pathology occupy leading positions in the practice of a doctor of any specialty especially in patients with HIV. Reproductive system is known to be the gateway for viruses. This fact could explain the severity of changes developing in the female reproductive system infected with HIV, in particular in the endometrium. The purpose of this study was to assess morphological changes in the endometrium caused by the combined effects of HIV infection and chronic alcoholism. Materials and methods: The study included sectional material taken from 60 women of reproductive age (20-40 years). They were all divided into two groups. The first group (30 people) consisted of HIV-positive individuals who, according to a survey of relatives and according to an autopsy (the main symptom is the presence of alcoholic cirrhosis of the liver), alcohol abuse was confirmed. The following parameters were determined: the average diameter of the endometrial glands (proliferative type), the minimum diameter of the endometrial glands (proliferative type), the maximum diameter of the endometrial glands (proliferative type), wall thickness (proliferative type), the relative volume of the epithelium (proliferative type), the average diameter of the glands (secretory type), the minimum diameter of the glands (secretory type), the maximum diameter of the glands (secretory type), the relative volume of the epithelium (secretory type), the thickness of the epithelium. Results. the average diameter of the endometrial glands (proliferative type) decreased from 51.71 ± 2.90 x 10-6 m in the comparison group to 39.42 ± 2.35 x 10-6 m in the HIV-infected group, which was 23.77%. The minimum diameter of the endometrial glands (proliferative type) reduced from 32.47 ± 1.83 x10-6 m to 27.13 ± 1.73x10-6 m (16.45%), the maximum diameter from 72.14 ± 2.21 x10-6 m to 63.84 ± 3.29 x10-6 m (11.5%). the relative volume of the epithelium (proliferative type) decreased by 5.41% (from 54.43 ± 1.79% in the study group to 49.02 ± 2.65% in the control group). The thickness of the uterine wall was also significantly reduced from 15.18 ± 1.60 x10-6 m to 14.52 ± 1.19 x10-6 m, which was 4.35%. The maximum volume of glands (secretory type) changed from 127.98 ± 2.10 x10-6 m to 97.18 ± 3.12 x10-6 m (24%). Changes by 3.6% were also observed when examining the wall thickness (from 13.02 ± 1.36 x10-6 m to 12.55 ± 1.68 x10-6 m). Conclusion. The study evaluated features of endometrial restructuring in alcohol-abusing HIV-infected women.

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“…The following indicators were determined: the thickness of the nonkeratinized stratified squamous epithelium (NSSE) in all groups of patients, the relative volumes of warts, expressed as a percentage [5], the distribution of the severity of CIN in the test material as a percentage among the entire test material. Statistical processing of the obtained results was performed using methods of variation statistics.…”

Section: Methodsmentioning

confidence: 99%

Morphometric peculiarities of the cervix uteri in immunodeficiency states

Lytvynenko

Gargin

2020

Rep. of Morph.

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Enhancing each other’s effects – HIV infection and the changes caused by alcohol abuse, trigger a chain of pathological reactions that sometimes lead to reversible and often irreversible pathological processes in the cervix uteri (CU). Local and general decrease in immunoresistance invariably leads to disturbance of physiological CU microbiome. Given all the above, the aim of our work was to identify pathological changes in CU that occur in HIV-infected women on the background of chronic alcoholism. Section material of 110 women of reproductive age from 20 to 40 years, which were divided into four groups, was studied. After the manufacture of micropreparations, a morphometric study was performed. Significant pathological changes in CU were revealed in HIV-infected women suffering from alcoholism. The maximum thickness of nonkeratinized stratified squamous epithelium (734.23±61.33 x10-6m) was characteristic of a group of HIV-infected women suffering from chronic alcoholism. In HIV-infected women, this figure is 3.14% lower and is 711.21±59.28 x10-6m. In women suffering from alcoholism without concomitant HIV infection, this figure is 697.8±47.88 x10-6m, which is 5% less than in the group with combined pathology. As expected, the lowest value was in the comparison group, where it was 527.23±44.37 x10-6m. There was a significant difference between the comparison group of HIV-infected women with alcoholism and the control group, which is 28.2%. In the studied material of HIV-infected patients, a high degree of distribution of the severity of cervical dysplasia was determined – 9.1%. Moderate and low degree, respectively, 19.42 and 37.12% in this group of subjects. When studying the degree of infiltration of the lamina propria mucosa in the study groups, it was found that the largest number of cases of severe infiltration (44.5%) was found in the group suffering from chronic alcoholism, and in the HIV groups no such case was detected. On the basis of the conducted research it is possible to assume the combined influence of the factors promoting development of pathological processes both in an epithelium, and in a mucous membrane of CU. Thus, HIV infection and alcohol abuse can exacerbate each other’s pathological effects and lead to pronounced pathomorphological changes in CU, namely: thickening of the mucosal epithelium due to frequent development of various types of warts, mucosal dysplasia and even severe cellular infiltration of the mucous membrane.

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Application of the computer vision system for evaluation of pathomorphological images

Cited by 42 publications

References 17 publications

Anatomical Predictions of Development of Rhinosinusitis and Its Complications

Anatomical Predictions of Development of Rhinosinusitis and Its Complications

Features of Endometrium Structure in Alcohol-Abusing Hiv-Infected Individuals

Morphometric peculiarities of the cervix uteri in immunodeficiency states

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