Application of Teeth Whitening LED for Prevention of Dental Caries : Antimicrobial Photodynamic Therapy Approach

Park, Choa; Park, Howon; Lee, Juhyun; Seo, Hyun‐Woo; Lee, Siyoung

doi:10.5933/jkapd.2020.47.1.70

Cited by 5 publications

(5 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The CFU counts immediately after treatment were significantly lower in Group II (PDT) than in Group I (negative control), thus verifying the antimicrobial ability of erythrosinemediated PDT on S. mutans. This is consistent with the results of previous studies [9,[11][12][13][14][15]. The American Society of Microbiology defines antimicrobial activity as a ≥3 log CFU/mL reduction from the starting inoculum [16].…”

Section: ⅳ Discussionsupporting

confidence: 91%

“…Studies have reported the use of erythrosine as a photosensitizer in PDT to exert antimicrobial effects against S. mutans cells in suspensions or biofilms [9,[11][12][13][14][15]. After antimicrobial treatment, residual bacteria induce the recovery of biofilm growth and CFU counts, indicating the possibility of reinfection.…”

Section: ⅳ Discussionmentioning

confidence: 99%

“…Park et al . [13] reported that PDT has a significant antimicrobial effect on S. mutans biofilm when the whitening LED used in homes was used as the light source. This further supports the potential and more frequent use of PDT with commercially available whitening home devices.…”

Section: ⅳ Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Recovery of Streptococcus Mutans Biofilm after Photodynamic Therapy with Erythrosine and LED Light Source

Shin¹,

Park²,

Lee³

et al. 2022

THE JOURNAL OF THE KOREAN ACADEMY OF PEDTATRIC DENTISTRY

Self Cite

View full text Add to dashboard Cite

The aim of this study was to evaluate the effects of erythrosine-mediated photodynamic therapy (PDT) on Streptococcus mutans biofilm recovery by counting its colony-forming units (CFUs) and via confocal laser scanning microscopy analysis at different time points following PDT. In PDT, photosensitizer was an erythrosine. S. mutans ATCC25175 biofilms were irradiated using an LED curing light. Chlorhexidine (CHX) was used as positive control. After each antimicrobial treatment, samples were cultured to allow biofilm recovery. Viability was measured by calculating the CFU counts after treatment and after every 3 hours for up to 24 hours. Immediately after treatment, the PDT and CHX groups showed equally significant decreases in S. mutans CFU counts compared to the negative control. After 12 hours of reculture, the PDT group showed no significant difference in the decrease in CFU count compared to the negative control, whereas the CHX group showed significantly lower CFU counts throughout the 24-hour period. Erythrosine-mediated PDT can effectively inhibit S. mutans biofilm formation. However, biofilm recovery occurred earlier in the CHX group after PDT. This study provides insights into the clinical effectiveness of PDT in preventing dental caries.

show abstract

Section: ⅳ Discussionsupporting

confidence: 91%

Section: ⅳ Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Recovery of Streptococcus Mutans Biofilm after Photodynamic Therapy with Erythrosine and LED Light Source

Shin¹,

Park²,

Lee³

et al. 2022

THE JOURNAL OF THE KOREAN ACADEMY OF PEDTATRIC DENTISTRY

Self Cite

View full text Add to dashboard Cite

show abstract

“…The PDT group demonstrated a significantly reduced number of S. mutans microorganisms compared to the control and EDTA groups. This result supports the effectiveness of PDT against cariogenic bacteria, consistent with prior research [15][16][17]32,33]. However, PDT is less effective when dealing with mature biofilm state.…”

Section: A B C Dsupporting

confidence: 91%

Enhancing the Antibacterial Effect of Erythrosine-Mediated Photodynamic Therapy with Ethylenediamine Tetraacetic Acid

Choi,

Kim,

Lee

et al. 2024

J Korean Acad Pediatr Dent

Self Cite

View full text Add to dashboard Cite

This study evaluated the additive impact of ethylenediamine tetraacetic acid (EDTA) on erythrosine-mediated photodynamic therapy (PDT) against Streptococcus mutans (S. mutans) biofilm by measuring colony-forming units and applying confocal laser scanning microscopy. Fifty-six bovine incisors, free from dental caries or structural defects, were utilized in this study. Dentin specimens were created by cutting with a low-speed diamond disk under a continuous flow of water, resulting in dimensions of 6.0 mm × 3.0 mm × 2.0 mm. The specimens were categorized into 4 groups: Control, EDTA, PDT, and EDTA + PDT. S. mutans ATCC 25175 was employed to establish biofilm on the dentin specimens. A 17% EDTA solution was applied for 1 min. For PDT, erythrosine served as the photosensitizer. Finally, a light-emitting diode source (385 - 515 nm) was employed in this study. The PDT group exhibited a significantly lower bacterial count than both the control and EDTA groups (p < 0.001). The EDTA + PDT group demonstrated a significantly reduced bacterial count compared to the other 3 groups (p < 0.001). This study demonstrated that EDTA enhances the antimicrobial efficacy of PDT on S. mutans biofilm. Even at a low concentration of photosensitizer, the combination of EDTA and PDT yields a significant antibacterial effect.

show abstract

“…It reduces the growth of Streptococcus mutans which ultimately prevents dental caries. This treatment will allow full arch irradiation 24 .…”

Section: Prevention Of Dental Cariesmentioning

confidence: 99%

Review on Caries Preventive Effect of Fluoride Toothpaste

2020

IJFMT

View full text Add to dashboard Cite

Dental caries is defined as localized destruction of tooth tissue, mainly due to bacterial action causing demineralized foci on peripheral surfaces. Normally, children have the habit of brushing their teeth once a day using fluoridated toothpaste. Due to this,there is less decay of tooth in them, as fluoride being a mineral prevents tooth decay. There is a relationship between fluoride toothpaste and dental caries, if a toothpaste having 1000ppm of fluoride content, is associated with less decay of tooth, so the fluoride has caries preventive effect. The aim of the review is to find out the role of fluoride in caries preventive effect, to know fluoride toothpastes correct concentration to avoid fluorosis and other fluoride related ailments and finally to understand the advantages of fluoride toothpaste as preventive effect of dental caries. This research was conceived as scoping literature review. This review has accessed existing reviews and researches in the last decade mostly, through PMC database, MeSH, Google Scholar, Pubmed, Medline, CrossRef and the search terms included were 'dental caries', 'fluoride toothpaste', 'caries preventive effect', 'fluoride'. Considered research was limited to manuscripts related to English, dental caries, fluoride toothpaste (as caries preventive effect) and this review did not include or consider other oral problems, other preventive methods of dental caries, natural components that prevent caries attack. The description of included studies for the review is tabulated. The role of fluoride in dental caries, its correct concentration in fluoride toothpaste is known and the preventive effect of fluoride toothpaste on dental caries is well understood through this review. With these general guidelines, there is more possibility of preventing dental caries and excessive fluoride will not lead to fluorosis due to awareness of correct concentration of fluoride in fluoride toothpaste.

show abstract

Application of Teeth Whitening LED for Prevention of Dental Caries : Antimicrobial Photodynamic Therapy Approach

Cited by 5 publications

References 25 publications

Recovery of Streptococcus Mutans Biofilm after Photodynamic Therapy with Erythrosine and LED Light Source

Recovery of Streptococcus Mutans Biofilm after Photodynamic Therapy with Erythrosine and LED Light Source

Enhancing the Antibacterial Effect of Erythrosine-Mediated Photodynamic Therapy with Ethylenediamine Tetraacetic Acid

Review on Caries Preventive Effect of Fluoride Toothpaste

Contact Info

Product

Resources

About