Application of Pfitzinger Reaction to the Facile One‐Pot Access of the Novel (5,6‐b)‐Quinolino‐8‐carboxylic‐acid‐Annulated Analogs of (2,3‐d)‐Azepino‐benzimidazol‐2,6‐diones of Medicinal Interest

Abstract

The potential of the Pfitzinger reaction has been explored to provide an expedient protocol to the synthesis of novel (5,6‐b)‐quinolino‐8‐carboxylic acid annulated analogues of (2,3‐d)‐azepino benzimidazol‐2,6‐diones 6a, 6b, 6c, 6d, 6e, 6f, 6g from (2,3‐d)‐azepino‐benzimidazol‐2,6,9‐triones 4 and isatins 5a, 5b, 5c, 5d, 5e, 5f, 5g.