Application of peripherally inserted central catheter in acute myeloid leukaemia patients undergoing induction chemotherapy

Chen, M.-H.; Hwang, Wen-Li; Chang, Kuang-Hsi; Chiang, Ling-Chun; Teng, Chieh Lin Jerry

doi:10.1111/ecc.12627

Cited by 12 publications

(8 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The PICC increased the quality of life in these patients during the chemotherapy period. Bacteremia in patients with PICCs was comparable to that of other IV lines, suggesting that PICC use is feasible in this patient population [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

Correlation of Positive Blood Cultures with Peripherally Inserted Central Catheter Line Infection in Oncology Patients

Platanaki¹,

Zareifopoulos²,

Lagadinou³

et al. 2021

Cureus

View full text Add to dashboard Cite

Introduction: The use of peripherally inserted central catheter (PICC) lines offers several advantages compared to traditional central venous catheters (CVCs) as the insertion procedure is minimally invasive, they may be retained safely for longer periods of time, and their use is associated with fewer catheter-related infections. Their use in patients suffering from a malignant disease is common but may pose a greater risk of complications due to the severe immunosuppression associated with treatment. This study was conducted to evaluate the safety of PICC lines in this group. Methods: This was a retrospective study of oncology patients being treated in a Mediterranean tertiary center. Patients with PICC lines were enrolled in the study if a positive blood culture necessitated the removal of the PICC and subsequent culture of the PICC tip. A comparison was conducted between patients with positive and negative PICC cultures. Results: Thirty patients were included, four of whom had a positive PICC culture. The most commonly isolated pathogens were coagulase-negative Staphylococci and Corynebacteria. No statistically significant difference was noted in white blood cell (WBC) counts, C-reactive protein (CRP), and Michigan PICC central line associated bloodstream infection (MPC) score between the two groups. Staphylococcus epidermidis was the most commonly isolated pathogen. Discussion: Though limited by a small sample size and the retrospective design, the findings of this study seem to corroborate existing literature on the subject which suggests that the use of PICC lines in oncology patients is feasible and does not pose unacceptable risk. Further research is indicated to determine subgroups which may be at greater risk of PICC related infections.

show abstract

Section: Discussionmentioning

confidence: 99%

Correlation of Positive Blood Cultures with Peripherally Inserted Central Catheter Line Infection in Oncology Patients

Platanaki¹,

Zareifopoulos²,

Lagadinou³

et al. 2021

Cureus

View full text Add to dashboard Cite

show abstract

“…There are few reports of the PICC in patients with hematological disorders 2 , 4 – 7 , 18 – 21 . Most studies are single-institution studies and demonstrate that PICCs are safer than CVCs in terms of the risk of catheter-related complications and CRBSI.…”

Section: Discussionmentioning

confidence: 99%

“…Similarly, our findings also suggest that patients with progressive diseases may be at a higher risk for CRBSI. Previous studies included cases in which a PICC was inserted multiple times; however, the proportion of such cases in the entire study cohorts was limited to approximately 20% 4 – 7 , 18 – 21 , and the studies did not examine the direct impact of multiple catheter insertions on CRBSI risks. In our study, about 60% (390/651) of all PICC insertion cases were of multiple insertions.…”

Section: Discussionmentioning

confidence: 99%

Catheter-related bloodstream infection associated with multiple insertions of the peripherally inserted central catheter in patients with hematological disorders

Hashimoto

Hosoda

Omura

et al. 2021

Sci Rep

View full text Add to dashboard Cite

Patients with hematological disorders are treated with multiple cycles of chemotherapy. As a result, they often require multiple insertions of the peripherally inserted central catheter (PICC) for prolonged periods of time. Although PICCs have been widely used worldwide in various patients, the safety and feasibility of the multiple insertions of the PICC in this population have not been fully verified. We performed a retrospective analysis to clarify the relationship between complications and multiple PICC insertions in patients with hematological disorders who were treated with either chemotherapy or immunotherapy. A total of 651 PICCs were inserted in 261 patients with a median age of 66 years. Acute myeloid leukemia (AML) and non-Hodgkin's lymphoma were the most common diseases in our patient cohort. The total catheter days (CDs) was 29,485 days, with a median catheter duration of 30 days. The rate of catheter-related bloodstream infection (CRBSI) in our patient cohort at high rate of re-insertion was 2.0/1000 CDs. Although multiple PICC insertions were not a risk factor of CRBSI, our findings suggest that a prolonged catheter dwell time may be associated with CRBSI. AML was an important risk factor of CRBSI. While the PICC dwell time depends on the treatment cycle, our findings indicate that it should be limited to approximately 30 days and catheters may be removed and re-inserted as needed.

show abstract

“…The PICC increased the quality of life in these patients during chemotherapy period. Bacteremia in patients with PICCs was comparable to that of other IV lines, suggesting the usefulness of the PICCs [14].…”

Section: Literature Retrievedmentioning

confidence: 94%

Peripheral Inserted Central Catheter Use and Related Infections in Clinical Practice: A Literature Update

et al. 2019

View full text Add to dashboard Cite

Peripherally inserted central catheter (PICC) lines are commonly used by clinicians in daily practice. This strategy has been established the latest years as a common approach in many clinical conditions. Apart from their usefulness, PICC use is related to some complications. Aim of this review is to summarize all relevant publications regarding the PICC-related infection, as sepsis remains a high mortality syndrome. We conducted a PubMed search to identify all relevant publications referring to infective complications after insertion and use of PICC lines in hospitalized adult patients. A great number of publications suggest that PICC lines are widely used in the management of patients. The use of peripheral inserted central lines is related with a few complications, including bloodstream infections. Existing data mainly support their use in specific clinical conditions because of the low infectious rates. Some conflicting data also exist regarding PICC use, due to an unclear benefit from their use compared to other commonly used strategies. Although a number of complications, including bloodstream infections are related with insertion of PICC lines, their use has a promising role and can be used when indicated in a wide variety of clinical conditions, especially in specific categories of patients and prolonged periods.

show abstract

Application of peripherally inserted central catheter in acute myeloid leukaemia patients undergoing induction chemotherapy

Cited by 12 publications

References 18 publications

Correlation of Positive Blood Cultures with Peripherally Inserted Central Catheter Line Infection in Oncology Patients

Correlation of Positive Blood Cultures with Peripherally Inserted Central Catheter Line Infection in Oncology Patients

Catheter-related bloodstream infection associated with multiple insertions of the peripherally inserted central catheter in patients with hematological disorders

Peripheral Inserted Central Catheter Use and Related Infections in Clinical Practice: A Literature Update

Contact Info

Product

Resources

About