Application of percutaneous vertebroplasty and percutaneous kyphoplasty in treating Kümmell’s patients with different stages and postural correction status

Yu, Haiming; Li, Yizhong; Yao, Xuedong; Lin, Johnson; Pan, Yuancheng; Wang, Pei‐Wen

doi:10.1080/17434440.2020.1736039

Cited by 14 publications

(19 citation statements)

References 30 publications

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“…The surgical treatment was mainly minimally invasive vertebroplasty, which can immediately and effectively relieve the pain, stabilize the injured vertebra, and correct kyphosis by filling the vertebra with bone cement. 1,10 Because of the poor hardness and biocompatibility of PMMA, it has a high incidence of adjacent vertebral body and intravertebral fracture after operation for the treatment of osteoporotic vertebral body fracture in the elderly. 11 When the traditional bone cement is directly injected into the fracture space of the injured vertebral body of patients with Kummell's disease, it is easy to form an independent mass structure.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…7 For patients with Kummell's disease without spinal cord compression, surgical treatment is mainly given by percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP), which can effectively relieve patients' pain and re-store the height of vertebral body in time and correction of kyphosis. [8][9][10] Polymethylmethacrylate (PMMA) is a commonly used bone cement for PVP or PKP, which has a strong hardness and biological inertness. Such properties were considered as one of the major factors inducing the postoperative fracture rate of adjacent vertebral bodies and incidence of re-fractures in the treated vertebra.…”

Section: Introductionmentioning

confidence: 99%

“…For patients with Kummell’s disease without spinal cord compression, surgical treatment is mainly given by percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP), which can effectively relieve patients’ pain and re-store the height of vertebral body in time and correction of kyphosis. 8–10…”

Section: Introductionmentioning

confidence: 99%

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The clinical results of treating Kummell’s disease with mineralized collagen modified polymethyl methacrylate

Wang

Kou

et al. 2021

J Biomater Appl

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To investigate the clinical results of treating Kummell’s Disease by using mineralized collagen modified polymethyl methacrylate bone cement, 23 cases (23 vertebras) who sustained Kummell’s Disease treated with mineralized collagen modified polymethyl methacrylate bone cement from July 2017 to February 2019 were reviewed retrospectively. The visual analogue scale, vertebral body height, Cobb angle, CT values pre-operation and post-operation as well as incidence of complications were observed. All the patients were successfully followed up with an average period of 11.3 months (ranging from 6 to 12 months). The patients could ambulate on the second day after the operation. The visual analogue scale scores significantly decreased from two days after the operation to the last follow-up compared with that before the operation ( p < 0.05); the average vertebral height and local Cobb angle had significant recovery ( p < 0.05); the CT value of the treated vertebra significantly increased compared with that before the operation ( p < 0.05). Bone cement leakage occurred in one case, anterior edge leakage occurred in one case, and no clinical symptoms caused by bone cement leakage occurred. No re-fracture of the treated vertebral body or adjacent vertebral bodies were observed in the follow-ups. With good osteogenic activity and degradable absorption characteristics, mineralized collagen was compounded with the existing polymethyl methacrylate bone cement to reduce its strength in the vertebral body and enhance biocompatibility, the incidence of adjacent vertebral fractures and re-fractures within the injured vertebrae is significantly reduced, and good clinical results are obtained, which is worthy of popularization.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The clinical results of treating Kummell’s disease with mineralized collagen modified polymethyl methacrylate

Wang

Kou

et al. 2021

J Biomater Appl

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“…The treatment of Kümmell's disease is still challenging for most spinal surgeons.One reason is that there are several different stages of progression of Kümmell's disease, but the choice of surgical methods for cases of different stages is still controversial [3,4,5,[9][10][11].Especially for the patients with kyphosis,most opinions agree that in the treatment of kyphosis with neurological de cits the injured vertebrae should be removed by posterior vertebral column resection VCR to relieve spinal cord compression,then kyphosis should be corrected and spinal stability should be reconstructed [12][13][14][15][16][17],so as to obtain better clinical effects.However,as for Kümmell's disease with simple kyphosis,most of the literature focus on eliminating the unstable factors of injured vertebra,so as to relieve local chronic and refractory lower back pain [4,[18][19][20][21],neglecting the restoring of the normal alignment and sagittal balance of the spine.In order to further explore the treatment of Kümmell's disease with kyphosis or sagittal imbalance,and to relieve the clinical symptoms,Shandong Provincial Hospital took this retrospective study.For the treatment of kyphosis combined with neurological symptoms,most of the views agree with posterior VCR [5,[13][14][15][16],and the surgical scheme and technology are relatively mature.So these kind of cases were selected as the control group.For the treatment of simple local kyphosis,there is a lack of relevant literature reports to disscus the surgical effect and follow-up results of such procedures.So, such cases are considered as the treatment group.The follow-up results of the two groups were statistically analyzed to explore the e cacy of the recovery and maintenance of normal spinal alignment and sagittal balance in the surgical treatment of Kümmell's disease with kyphosis, and the necessity of such treatment.…”

Section: Radiographic and Clinical Outcomes Of Surgicalmentioning

confidence: 99%

Radiographic and Clinical Outcomes of Surgical Treatment of Kümmell’s Disease With Thoracolumbar Kyphosis: A Minimal Two-Year Follow-Up

Cheng

Wang

et al. 2021

Preprint

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Background: To evaluate the short to mid-term radiographic and clinical outcomes of the restoration of normal spinal alignment and sagittal balance in the treatment of Kümmell’s disease with thoracolumbar kyphosis. Methods: Between February 2016 and May 2018,30 cases of Kümmell’s disease with thoracolumbar kyphosis were divided into two groups (A and B) according to whether the kyphosis was combined with neurological deficits.All of the cases underwent surgical treatment to regain the normal spinal alignment and sagittal balance.And the radiographic outcomes and clinical results of these 30 patients were retrospectively evaluated.The sagittal imaging parameters including sagittal vertebral axis (SVA),thoracic kyphosis (TK),thoracolumbar kyphosis (TLK),lumbar lordosis (LL),pelvic incidence (PI),pelvic tilt (PT),and sacral slope (SS)of the whole spine before operation,immediately after operation,and the last follow-up of each group were measured and evaluated.The clinical results included the Oswestry Disability Index (ODI) and the Numerical Rating Scale (NRS) of the two groups .Results: The average follow-up period of group A and B were 34.2 and 38.7 months respectively.The parameters of both groups such as SVA,TLK,and thoracolumbar Cobb angle after surgery and at the last follow-up were significantly improved compared with those before surgery.The ODI and the NRS of the two groups at the last follow-up were also significantly improved. Conclusion: In the treatment of Kümmell’s disease with thoracolumbar kyphosis,to restore the normal alignment and sagittal balance can obtain a satisfactory radiographic and clinical short and medium-term effects.

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Comparison of Outcomes Between Percutaneous Vertebroplasty and Percutaneous Kyphoplasty for the Treatment of Kümmell’s Disease

Huang

Chang

Cheng

et al. 2021

Clinical Spine Surgery: A Spine Publication

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Study Design: A meta-analysis. Objective: The aim is to compare the efficacy of percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) in treating Kümmell’s disease (KD) without neurological deficits. Summary of Background Data: PVP and PKP are routine methods for the treatment of KD without neurological deficits; however, whether PVP or PKP is superior is a matter of debate. Materials and Methods: According to the Cochrane Handbook for Systematic Reviews of Interventions, PubMed, Embase, the Cochrane Library, and Web of Knowledge were searched for eligible randomized controlled trials or cohort studies. Two authors independently collected data and assessed the methodologic quality of the included studies. Intraoperative and postoperative clinical outcomes, cement leakage, refracture rate, and the costs during hospitalization were evaluated. Results: Five observational studies comparing 119 PVP and 128 PKP patients were included in qualitative and quantitative reviews. All of the included s studies had evidence of good quality, as assessed by the Newcastle-Ottawa scale. On the basis of meta-analysis the operation time [weighted mean difference: −10.65; 95% confidence interval (95% CI): −11.94 to −9.35; P<0.00001] and hospitalization cost (weighted mean difference: −2.38; 95% CI: −2.87 to −1.89; P<0.00001) were less for PVP, while the cement leakage rate was lower for PKP (odds ratio: 3.03; 95% CI: 1.58–5.82; P<0.001). Together, the data indicated that the differences in cement volume, visual analog scale score, Oswestry disability index score, Cobb angle, anterior vertebral height, and refracture rate were not significantly different. Conclusion: The findings of this study suggest that PVP and PKP are safe and effective for the treatment of KD. PVP required less operative time and was more affordable, but PKP was superior given the lower cement leakage rate. Additional high-quality randomized controlled trials designed to support these findings are warranted.

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Application of percutaneous vertebroplasty and percutaneous kyphoplasty in treating Kümmell’s patients with different stages and postural correction status

Cited by 14 publications

References 30 publications

The clinical results of treating Kummell’s disease with mineralized collagen modified polymethyl methacrylate

The clinical results of treating Kummell’s disease with mineralized collagen modified polymethyl methacrylate

Radiographic and Clinical Outcomes of Surgical Treatment of Kümmell’s Disease With Thoracolumbar Kyphosis: A Minimal Two-Year Follow-Up

Comparison of Outcomes Between Percutaneous Vertebroplasty and Percutaneous Kyphoplasty for the Treatment of Kümmell’s Disease

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