Application of partial least squares multivariate calibration for the determination of mixtures of carbaryl and thiabendazole in waters by transmitted solid phase spectrophosphorimetry

Flow injection analysis with on-line nylon powder extraction for room-temperature phosphorescence determination of thiabendazole

“…While the native fluorescence of TBZ has been known for more than two decades, few papers related to TBZ phosphorescence have been reported, and most of then refer to measurements in solution [11][12][13][14][15][16][17]. Although it was demonstrated that both filter paper and nylon disks are able to induce RTP emission of TBZ retained on their surfaces [12,13,17], RTP signals have not been detected when this analyte was retained in the supports which are usually employed in the implementation of flow-through optosensors for neutral molecules, such as C18 silica gel and non-ionic resins. Apparently, the immobilization in these materials is not efficient enough to prevent the non-radiative deactivation of the excited triplet state of TBZ.…”

Chemometrics Assisted Spectrophotometric Method for Simultaneous Determination of Certain Fluoroquinolones and Their Decarboxylated Degradants

“…Multivariate calibration methods applied to spectral data are being increasingly used for pharmaceutical analysis. [28][29][30][31][32][33][34][35] Classical least squares (CLS) analysis is one of the simplest multivariate methods that can be performed with easily accessible statistical software. In the present work we discuss the possibility of simultaneous determination of either LF or NF as representative examples of the commercial fluoroquinolones in presence of their decarboxylated degradation products by a simple, rapid and precise procedure, and subsequent application of the method to the analysis of laboratory prepared binary mixtures, laboratory degraded drug samples and some used and expired commercial formulations.…”

Multivariate Spectrophotometric Analysis of Certain Antihypertensive Binary Mixtures

“…Multivariate calibration methods applied to spectral data are being increasingly used for pharmaceutical analysis. [35][36][37][38][39][40] Classical least squares (CLS) analysis is one of the simplest multivariate methods that can be performed with easily accessible statistical software. In the present work we discuss the possibility of simultaneous analysis of combined formulations of reserpine with either hydrochlorothiazide or hydrofluomethiazide in certain antihypertension mixtures.…”