Application of omics techniques in forensic entomology research

Shao, Shuang; Yang, Lijun; Hu, Gengwang; Li, Liangliang; Wang, Yu; Tao, Luyang

doi:10.1016/j.actatropica.2023.106985

Cited by 4 publications

(1 citation statement)

References 169 publications

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“…Proteomics is a discipline that has seen a great evolution by expanding towards new technologies with greater possibilities for protein profiling and discovery of diagnostic biomarkers [ 22 ]. The interaction between proteins, metabolites, and interactors can modulate a large number of cellular processes, including metabolic pathways, growth signals, and cellular stress [ 23 , 24 ]. Therefore, the study of proteins and the integrated analysis of data with new proteomics strategies can offer a molecular view of various physiological and pathological conditions.…”

Section: Introductionmentioning

confidence: 99%

Exploring the Potential of Proteome Analysis as a Promising Tool for Evaluation of Sudden Cardiac Death (SCD) in Forensic Settings: A Literature Review

Sacco,

Gualtieri,

Calanna

et al. 2023

IJMS

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Sudden cardiac death (SCD) represents a global emergency, with a high number of cases affecting all age groups every year. The prevention of these fatal events requires an accurate knowledge of etiology and pathogenesis, which can vary. Autopsy is an indispensable tool in cases of SCD for diagnostic purposes, as well as for judicial and preventive purposes for family members. Despite the completion of all routine post-mortem investigations, it is often complicated for the forensic pathologist to define the triggering cause of these events. The study of the proteome is proving to be extremely promising in the field of human cardiovascular disease. This paper aims to offer a literature review on the study of the proteome in post-mortem cadaveric biological samples obtained from SCD cases. The aim of this work is to outline the state of the art of the scientific advances that protein analysis can offer in the diagnosis of SCD and the limits that various studies have traced up to now. In conclusion, the work defines the future perspectives of this field in SCD, suggesting strategies to overcome the reported limits and improve the diagnostics of these events.

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Section: Introductionmentioning

confidence: 99%

Exploring the Potential of Proteome Analysis as a Promising Tool for Evaluation of Sudden Cardiac Death (SCD) in Forensic Settings: A Literature Review

Sacco,

Gualtieri,

Calanna

et al. 2023

IJMS

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Mitochondrial genome comparison and phylogenetic position of Fannia pusio among the Calyptratae flies

Durango-Manrique,

López-Rubio,

Gutiérrez

et al. 2024

Heliyon

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HOFE: an interactive forensic entomological database

Liu,

Qu,

Luo

et al. 2024

Database

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The significance of entomological evidence in inferring the time, location and cause of death has been demonstrated both theoretically and practically. With the advancement of sequencing technologies, reports have emerged on necrophagous insects’ nuclear genomes, transcriptomes, proteomes and mitochondrial genomes. However, within the field of forensic entomology, there is currently no available database that can integrate, store and share the resources of necrophagous insects. The absence of a database poses an inconvenience to the application of entomological evidence in judicial practice and hampers the development of the forensic entomology discipline. Given this, we have developed the Home Of Forensic Entomology database, encompassing 10 core functional modules: Home, Browse, Mitochondria, Proteome, JBrowse, Search, BLAST, Tools, Case base and Maps. Notably, the ‘Tools’ module enables multiple sequence alignment analysis (Muscle), homologous protein prediction (Genewise), primer design (Primer), large-scale genomic analysis (Lastz), Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analysis, as well as expression profiling (PCA Analysis, Hcluster and Correlation Heatmap). In addition, the present database also works as an interactive platform for researchers by sharing forensic entomological case reports and uploading data and material. This database provides potential visitors with a comprehensive function for multi-omics data analysis, offers substantial references to researchers and criminal scene investigators and facilitates the utilization of entomological evidence in court. Database URL: http://ihofe.com/

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Application of omics techniques in forensic entomology research

Cited by 4 publications

References 169 publications

Exploring the Potential of Proteome Analysis as a Promising Tool for Evaluation of Sudden Cardiac Death (SCD) in Forensic Settings: A Literature Review

Exploring the Potential of Proteome Analysis as a Promising Tool for Evaluation of Sudden Cardiac Death (SCD) in Forensic Settings: A Literature Review

Mitochondrial genome comparison and phylogenetic position of Fannia pusio among the Calyptratae flies

HOFE: an interactive forensic entomological database

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