Application of nonlinear phenomena induced by focused ultrasound to bone imaging

The effect of yield damage on the viscoelastic properties of cortical bone tissue as measured by dynamic mechanical analysis

“…62 Furthermore, there is evolving technology that is promising for application of vibration-based methods to bone in vivo. 63 While it is not the purpose of this paper to outline these methodologies for in vivo use, the presence of such effort indicates that the basic science developed in this area will find clinical application in future.…”

Transient displacement induced in shear wave elastography: Comparison between analytical results and ultrasound measurements

“…Several techniques which use the acoustic radiation force have been developed since then. Greenleaf and Fatemi developed the vibro-acoustography method [5][6][7]. They used an alternative radiation force generated by two intersecting continuous ultrasound beams to remotely vibrate an object at an arbitrary low frequency, the acoustic response being detected by an external hydrophone.…”

Acoustic radiation force impulse imaging of thermally- and chemically-induced lesions in soft tissues: preliminary ex vivo results

“…The feasibility of using acoustic radiation force methods to detect tissue mechanical properties has been investigated by several groups (Alizad et al 2002;Calle et al 2003;Fatemi and Greenleaf, 1998;Konofagou et al 2001;Sarvazyan et al 1998;Sugimoto et al 1990;Viola and Walker 2003) and has been demonstrated in vivo by our group (Nightingale et al 2002a(Nightingale et al , 2002b(Nightingale et al , 2002c. We demonstrate ARFI imaging's ability to detect the presence, size and boundaries of stiffened lesions, including those created during tumor ablation processes.…”