Application of nanoparticles in breast cancer treatment: a systematic review

Bourang, Shima; Noruzpour, Mehran; Jahanbakhsh Godekahriz, Sodabeh; Ebrahimi, Hossein Ali Ca; Amani, Amin; Asghari Zakaria, Rasool; Yaghoubi, Hashem

doi:10.1007/s00210-024-03082-y

Naunyn-Schmiedeberg's Arch Pharmacol

2024

DOI: 10.1007/s00210-024-03082-y

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Application of nanoparticles in breast cancer treatment: a systematic review

Shima Bourang,

Mehran Noruzpour,

Sodabeh Jahanbakhsh Godekahriz

et al.

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Emerging Applications of Nanoparticles in the Diagnosis and Treatment of Breast Cancer

Oehler,

Rajapaksha,

Albrecht

2024

JPM

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Breast cancer remains the most prevalent cancer among women worldwide, driving the urgent need for innovative approaches to diagnosis and treatment. This review highlights the pivotal role of nanoparticles in revolutionizing breast cancer management through advancements of interconnected approaches including targeted therapy, imaging, and personalized medicine. Nanoparticles, with their unique physicochemical properties, have shown significant promise in addressing current treatment limitations such as drug resistance and nonspecific systemic distribution. Applications range from enhancing drug delivery systems for targeted and sustained release to developing innovative diagnostic tools for early and precise detection of metastases. Moreover, the integration of nanoparticles into photothermal therapy and their synergistic use with existing treatments, such as immunotherapy, illustrate their transformative potential in cancer care. However, the journey towards clinical adoption is fraught with challenges, including the chemical feasibility, biodistribution, efficacy, safety concerns, scalability, and regulatory hurdles. This review delves into the current state of nanoparticle research, their applications in breast cancer therapy and diagnosis, and the obstacles that must be overcome for clinical integration.

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Emerging Applications of Nanoparticles in the Diagnosis and Treatment of Breast Cancer

Oehler,

Rajapaksha,

Albrecht

2024

JPM

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show abstract

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Application of nanoparticles in breast cancer treatment: a systematic review

Cited by 1 publication

References 333 publications

Emerging Applications of Nanoparticles in the Diagnosis and Treatment of Breast Cancer

Emerging Applications of Nanoparticles in the Diagnosis and Treatment of Breast Cancer

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