Application of Nanobiosensor in Health Care Sector

Preetam, Subham; Dash, Lipsa; Sarangi, Suman Sudha; Sahoo, Mitali Madhusmita; Pradhan, Arun Kumar

doi:10.1007/978-981-16-2516-9_14

Cited by 15 publications

(13 citation statements)

References 114 publications

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“…There isn't a prominent enzymatic scavenging mechanism in the body that can eliminate hydroxyl radicals. Antioxidants are the only protection against hydroxyl radicals [308][309][310][311]. Chemicals exposed to radiation may result in the production of ROS, which then causes lipid peroxidation.…”

Section: Potential Nano-toxicity Of Nano-systems Used For Anti-microb...mentioning

confidence: 99%

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Nanotheranostics to target antibiotic-resistant bacteria: Strategies and applications

et al. 2023

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Section: Potential Nano-toxicity Of Nano-systems Used For Anti-microb...mentioning

confidence: 99%

“…Tumor cells produce more ROS and endure oxidative stress than normal cells do, which promotes mutations, genetic changes, cell expansion, and cell death. Chemicals that forage ROS are, therefore likely candidates for use as tumor therapies [308][309][310][311].…”

Section: Potential Nano-toxicity Of Nano-systems Used For Anti-microb...mentioning

confidence: 99%

Nanotheranostics to target antibiotic-resistant bacteria: Strategies and applications

et al. 2023

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“…Here, the polluted wastewater bodies provide a nutrient-rich environment, i.e., micronutrients such as vitamins like thiamine and cyanocobalamin and macronutrients such as salts of PO 4 3− and NO 3 − with NH 4 + , Na, Ca, and K for the algal growth ( Figure 10 ). Thereby the cultivation of algal cells in wastewater helps to remove the pollutants by adsorbing them [ 95 , 96 ]. There are several approaches for isolating algal biomass, either physically by centrifugation, air floatation, and sedimentation, or chemically by flocculation, nevertheless their higher cost for large-scale treatment.…”

Section: Integrated Microbial and Nanotechnological Approaches For Wa...mentioning

confidence: 99%

“…In a study, the reverse osmosis membrane outer layer of polyvinyl alcohol (PVA) was coated with TiO 2 , resulting in fouling reduction by introducing self-cleaning through UV irradiation [ 53 ]. Similarly, the hydrophilicity of the membrane surface was enhanced with antifouling properties and water flux by blending the PSF hollow fibre membranes (HFMs) with multi-walled carbon nanotubes (MWNTs) [ 84 , 85 , 86 , 87 , 88 , 89 , 90 , 91 , 92 , 93 , 94 , 95 , 96 , 97 , 98 , 99 ]. Metallic photocatalysis TiO 2 has been investigated for various applications for pollution control systems and self-cleaning surfaces of the reactor system (Cruz et al, 2020).…”

Section: Integrated Microbial and Nanotechnological Approaches For Wa...mentioning

confidence: 99%

Exploring Microbial-Based Green Nanobiotechnology for Wastewater Remediation: A Sustainable Strategy

Malik

Dhasmana

Preetam³

et al. 2022

Nanomaterials

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Water scarcity due to contamination of water resources with different inorganic and organic contaminants is one of the foremost global concerns. It is due to rapid industrialization, fast urbanization, and the low efficiency of traditional wastewater treatment strategies. Conventional water treatment strategies, including chemical precipitation, membrane filtration, coagulation, ion exchange, solvent extraction, adsorption, and photolysis, are based on adopting various nanomaterials (NMs) with a high surface area, including carbon NMs, polymers, metals-based, and metal oxides. However, significant bottlenecks are toxicity, cost, secondary contamination, size and space constraints, energy efficiency, prolonged time consumption, output efficiency, and scalability. On the contrary, green NMs fabricated using microorganisms emerge as cost-effective, eco-friendly, sustainable, safe, and efficient substitutes for these traditional strategies. This review summarizes the state-of-the-art microbial-assisted green NMs and strategies including microbial cells, magnetotactic bacteria (MTB), bio-augmentation and integrated bioreactors for removing an extensive range of water contaminants addressing the challenges associated with traditional strategies. Furthermore, a comparative analysis of the efficacies of microbe-assisted green NM-based water remediation strategy with the traditional practices in light of crucial factors like reusability, regeneration, removal efficiency, and adsorption capacity has been presented. The associated challenges, their alternate solutions, and the cutting-edge prospects of microbial-assisted green nanobiotechnology with the integration of advanced tools including internet-of-nano-things, cloud computing, and artificial intelligence have been discussed. This review opens a new window to assist future research dedicated to sustainable and green nanobiotechnology-based strategies for environmental remediation applications.

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“…Silicon nanowires are being developed as ultra-sensitive mark-free sensor technology. After being modified with antibodies, silicon nanowires transistors can detect a single virus (Preetam et al, 2022).…”

Section: Nanotechnology-based Biosensorsmentioning

confidence: 99%

Application of nanomaterials against SARS-CoV-2: An emphasis on their usefulness against emerging variants of concern

Iqbal

Khan

Ali

et al. 2022

Front. Nanotechnol.

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Researchers are now looking to nanomaterials to fight serious infectious diseases that cause outbreaks and even pandemics. SARS-CoV-2 brought chaos to almost every walk of life in the past 2 years and has challenged every available treatment method. Although vaccines were developed in no time against it, the most pressing issue was the emergence of variants of concern arising because of the rapidly evolving viral strains. The higher pathogenicity and, in turn, the higher mortality rate of infections caused by these variants renders the existing vaccines less effective and the effort to produce further vaccines a costly endeavor. While several techniques, such as immunotherapy and repurposed pharmaceutical research, are being studied to minimize viral infection, the fundamentals of nanotechnology must also be considered to enhance the anti-SARS-CoV-2 efforts. For instance, silver nanoparticles (AgNPs) have been applied against SARS-CoV-2 effectively. Similarly, nanomaterials have been tested in masks, gloves, and disinfectants to aid in controlling SARS-CoV-2. Nanotechnology has also contributed to diagnoses such as rapid and accurate detection and treatment such as the delivery of mRNA vaccines and other antiviral agents into the body. The development of polymeric nanoparticles has been dubbed a strategy of choice over traditional drugs because of their tunable release kinetics, specificity, and multimodal drug composition. Our article explores the potential of nanomaterials in managing the variants of concern. This will be achieved by highlighting the inherent ability of nanomaterials to act against the virus on fronts such as inhibition of SARS-CoV-2 entry, inhibition of RNA replication in SARS-CoV-2, and finally, inhibition of their release. In this review, a detailed discussion on the potential of nanomaterials in these areas will be tallied with their potential against the current and emerging future variants of concern.

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Application of Nanobiosensor in Health Care Sector

Cited by 15 publications

References 114 publications

Nanotheranostics to target antibiotic-resistant bacteria: Strategies and applications

Nanotheranostics to target antibiotic-resistant bacteria: Strategies and applications

Exploring Microbial-Based Green Nanobiotechnology for Wastewater Remediation: A Sustainable Strategy

Application of nanomaterials against SARS-CoV-2: An emphasis on their usefulness against emerging variants of concern

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