Application of multiplex realtime PCR detection for hemorrhagic fever syndrome viruses

Choi, Yoonhyuk; Kim, Younghee

doi:10.1016/j.jiph.2023.10.012

Cited by 2 publications

(2 citation statements)

References 47 publications

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“…When VHF of unknown etiology is introduced, it is anticipated that the multiplex virus test method devised in this study will be utilized for quarantine and public health [ 226 ]. .…”

Section: Future and Landscapementioning

confidence: 99%

Recent Advances in Crimean-Congo Hemorrhagic Fever Virus Detection, Treatment, and Vaccination: Overview of Current Status and Challenges

Muzammil,

Rayyani,

Abbas Sahib

et al. 2024

Biol Proced Online

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Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne virus, and zoonosis, and affects large regions of Asia, Southwestern and Southeastern Europe, and Africa. CCHFV can produce symptoms, including no specific clinical symptoms, mild to severe clinical symptoms, or deadly infections. Virus isolation attempts, antigen-capture enzyme-linked immunosorbent assay (ELISA), and reverse transcription polymerase chain reaction (RT-PCR) are all possible diagnostic tests for CCHFV. Furthermore, an efficient, quick, and cheap technology, including biosensors, must be designed and developed to detect CCHFV. The goal of this article is to offer an overview of modern laboratory tests available as well as other innovative detection methods such as biosensors for CCHFV, as well as the benefits and limits of the assays. Furthermore, confirmed cases of CCHF are managed with symptomatic assistance and general supportive care. This study examined the various treatment modalities, as well as their respective limitations and developments, including immunotherapy and antivirals. Recent biotechnology advancements and the availability of suitable animal models have accelerated the development of CCHF vaccines by a substantial margin. We examined a range of potential vaccines for CCHF in this research, comprising nucleic acid, viral particles, inactivated, and multi-epitope vaccines, as well as the present obstacles and developments in this field. Thus, the purpose of this review is to present a comprehensive summary of the endeavors dedicated to advancing various diagnostic, therapeutic, and preventive strategies for CCHF infection in anticipation of forthcoming hazards. Graphical Abstract

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“…When VHF of unknown etiology is introduced, it is anticipated that the multiplex virus test method devised in this study will be utilized for quarantine and public health [ 226 ]. .…”

Section: Future and Landscapementioning

confidence: 99%

Recent Advances in Crimean-Congo Hemorrhagic Fever Virus Detection, Treatment, and Vaccination: Overview of Current Status and Challenges

Muzammil,

Rayyani,

Abbas Sahib

et al. 2024

Biol Proced Online

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“…Furthermore, a multiplex real-time PCR assay was developed to detect 17 hemorrhagic fever syndrome viruses, which also performed well and seems well suited to public health applications [35]. Lapa and colleagues (2024) provide an insight review on the diagnostics of Rift Valley Fever Virus [32].…”

Section: Introductionmentioning

confidence: 99%

Rift Valley Fever, an Emerging Viral Zoonosis Worthy of Increased Attention

van den Hurk,

Velayudhan*

2024

J Biomed Res Environ Sci

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Rift Valley Fever (RVF) is an emerging zoonotic disease transmitted by mosquitoes. Though North America is considered free of RVF, surveillance and monitoring of high-risk groups would be important for early detection of potential introduction of the disease. Rift Valley Fever Virus (RVFV) is an RNA virus that primarily affects livestock but can also infect humans with varying severity of infection. Though the disease is mainly prevalent in African countries, the vectors involved in the transmission of RVF are present in many regions in the American and European continents. So, the potential for emergence of this disease in new geographical locations is imminent. There is an unmet need for development of improved research and diagnostic tools to further investigate and manage RVF and to better understand its significance from a One Health perspective.

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Application of multiplex realtime PCR detection for hemorrhagic fever syndrome viruses

Cited by 2 publications

References 47 publications

Recent Advances in Crimean-Congo Hemorrhagic Fever Virus Detection, Treatment, and Vaccination: Overview of Current Status and Challenges

Recent Advances in Crimean-Congo Hemorrhagic Fever Virus Detection, Treatment, and Vaccination: Overview of Current Status and Challenges

Rift Valley Fever, an Emerging Viral Zoonosis Worthy of Increased Attention

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