Application of molecularly imprinted polymers to solid-phase extraction of compounds from environmental and biological samples

Caro, Ester; Marcé, Rosa María; Borrull, Francesc; Cormack, Peter A. G.; Sherrington, David C.

doi:10.1016/j.trac.2005.05.008

Cited by 311 publications

(109 citation statements)

References 56 publications

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“…They have demonstrated high specificity by being capable of repeated binding and re-binding to analytes of interest in the presence of other closely related compounds hence their incorporation as SPE sorbents (Caro et al, 2006;Kandimalla, 2004;Qiao et al, 2006). In aqueous mobile phases, MIPs display reversed phase interactions.…”

Section: Molecularly Imprinted Polymers (Mips)mentioning

confidence: 99%

Modern Sample Preparation Techniques for Pesticide Analysis

Mmualefe¹,

Mpofu²,

Torto³

2011

Pesticides in the Modern World - Trends in Pesticides Analysis

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Section: Molecularly Imprinted Polymers (Mips)mentioning

confidence: 99%

Modern Sample Preparation Techniques for Pesticide Analysis

Mmualefe¹,

Mpofu²,

Torto³

2011

Pesticides in the Modern World - Trends in Pesticides Analysis

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“…So far, no mention has been made of more specialized SPE phases such as restricted-access media (RAM), molecular imprinted polymers (MIP), immunoaffinity extraction (IAE) phases and other class-or compound-selective sorbents. This is because almost all applications which utilize one of these selective types of sorbent use LC for subsequent analysis (see, e.g., [207,208]). Although this is, therefore, an area largely beyond the scope of the present review, a few pertinent examples are included in Table 8.…”

Section: On-line Microcontaminantsmentioning

confidence: 99%

Modern Methods of Sample Preparation for GC Analysis

Koning¹,

Janssen

Brinkman

2009

Chroma

115

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Today, a wide variety of techniques is available for the preparation of (semi-) solid, liquid and gaseous samples, prior to their instrumental analysis by means of capillary gas chromatography (GC) or, increasingly, comprehensive two-dimensional GC (GC 9 GC). In the past two decades, a large number of 'modern' sample-preparation techniques has been introduced, which have partly superseded their 'classical' counterparts. These novel techniques include off-line and on-line (sometimes semi-or fully automated) procedures, and exhaustive extraction as well as equilibrium techniques. In order to improve overall performance, aspects such as essentially organic solvent-less approaches, large-volume injection and miniaturization receive increasing attention. In most recent applications, mass spectrometric or element-selective detection have been used. The present review discusses the advantages and disadvantages, and relative performance, of most of the modern samplepreparation techniques and cites a number of illustrative applications for each of them.

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“…However, traditional sorbents of SPE like C 18 silica gel are mainly based on non-specific adsorption rather than selective molecular recognition. Currently, molecularly imprinted polymers (MIPs) as SPE sorbents have attracted considerable attention for ease of use and high binding selectivites [19]. However, the drawback of the MIP technique is the leakage of template molecules from the polymer matrix, which may cause false-positive results especially for trace analysis [20].…”

Section: Introductionmentioning

confidence: 99%

Determination of hydroxylated polychlorinated biphenyls by offline solid-phase extraction-liquid chromatography–tandem mass spectrometry using a molecularly imprinted polymer as a sorbent for sample preconcentration

Liang

Zhao

et al. 2015

Talanta

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a b s t r a c tHydroxylated polychlorinated biphenyls (OH-PCBs) can be detected by liquid chromatography-mass spectrometry coupled to solid-phase extraction (SPE) using a dummy molecularly imprinted polymer (DMIP) as a sorbent. The DMIP is prepared by using an analogue of OH-PCBs (i.e., 4, 4-dihydroxybiphenyl) as a dummy template, to avoid the leakage of the target molecules. The DMIP-SPE sorbent shows good recoveries for OH-PCBs at pH 11 due to the charge-assisted hydrogen bondings between OH-PCBs and the DMIP. It has been found that the DMIP is much more effective and selective than the traditional C 18 -SPE method. The sample pH, polymer dosage, elution solvent and volume have been optimized for higher recoveries. Under the optimum experimental conditions, OH-PCBs can be detected in the linear concentration range of 0.05-1.0 pM, with the detection limits ranging from 11 fM to 82 fM for 4′-OH-CB 9, 4′-OH-CB 30, 4′-OH-CB 61, 4′-OH-CB 106 and 4′-OH-CB 112. The proposed system has been successfully applied to the determination of trace OH-PCBs in spiked water samples with recoveries in the range of 89-110%.

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Application of molecularly imprinted polymers to solid-phase extraction of compounds from environmental and biological samples

Cited by 311 publications

References 56 publications

Modern Sample Preparation Techniques for Pesticide Analysis

Modern Sample Preparation Techniques for Pesticide Analysis

Modern Methods of Sample Preparation for GC Analysis

Determination of hydroxylated polychlorinated biphenyls by offline solid-phase extraction-liquid chromatography–tandem mass spectrometry using a molecularly imprinted polymer as a sorbent for sample preconcentration

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