Application of molecularly imprinted polymers (MIPs) as environmental separation tools

Abstract

This review is structured to outline the applications of MIPs as environmental separation tools and assess the role of functional groups as a parameter influencing MIP performance.

Oxidative Stress in Spinocerebellar Ataxia Type 3 and Its Attenuation by Herbal Remedies in Traditional Chinese Medicine: A Systematic Review

“…Therefore, interfering substances may need to be removed through column chromatography, droplet counter-current chromatography, and solid-phase extraction. Moreover, molecularly imprinted polymers that possess specialized binding capabilities for targeted analytes can be utilized owing to their thermochemical stability, reusability, and exceptional selectivity and recognition capabilities, enabling the detection of specific target molecules [ 166 ].…”

Synthesis of a Multi-Template Molecular Imprinted Bulk Polymer for the Adsorption of Non-Steroidal Inflammatory and Antiretroviral Drugs

“…In contrast, molecularly imprinted polymers (MIPs) present a distinct advantage in selective adsorption purposes. MIPs are synthetic materials designed with specific molecular recognition sites that can selectively bind to target compounds, such as pharmaceuticals [20]. Their customizability and high selectivity make MIPs promising candidates for the removal of ARV drugs, NSAIDs, and other pharmaceutical pollutants from water sources [21,22].…”

“…To prepare these MIPs, various important materials are needed, such as a functional monomer and cross-linking agent. A functional monomer is a molecule that is known to be responsible for the binding interactions at imprinted binding sites [20,23]. A functional monomer is utilized in excess compared to moles of a template in a non-covalent imprinting technique to promote the production of template-functional monomer assemblies [24].…”

“…The functional monomer in the current study was 2-vinyl pyridine. This monomer can create hydrogen bonding with the carboxylic group of the target molecules and plays a crucial role in the formation of selective binding sites within the MIPs, facilitating the recognition and separation of the target molecule [20]. The functional groups present on the template molecule interact with complementary functional groups within the polymer matrix, in this case, the nitrogen in the pyridine, leading to specific binding and recognition of the target molecule based on chemical compatibility.…”

Design of poly(N-isopropylacrylamide) coated MnO2 nanoparticles for thermally regulated catalytic decomposition of H2O2

“…30 Polymers synthesized via controlled radical polymerization ‘CRP’ methods (atom transfer radical polymerization (ATRP), 31–34 nitroxide mediated polymerization (NMP), 35–37 and reversible addition–fragmentation chain transfer (RAFT) polymerization) are extensively used for the modification of inorganic NPs as these methods provide ease of synthesis of polymers with precise molar masses, diverse compositions, and a high degree of chain-end functionality. 38–44 Among the CRP methods, RAFT polymerization is very appealing because of its compatibility with a vast array of monomers, mild reaction conditions and because it avoids the use of metal catalysts. 43,45 Thermoresponsive LCST polymers show a phase transition due to the change in entropy of solvation of the polymeric chain in aqueous solution as temperature alters.…”