Application of molecular methods in optimizing clinical management of patients with pulmonary multidrug resistant tuberculosis in Tanzania
Peter Mbelele
Abstract:Rifampicin or multidrug-resistant tuberculosis (RR/MDR-TB) accounts for considerable morbidity and mortality. Differences among Mycobacterium tuberculosis complex (MTBC) species may predict drug-resistance or treatment success. This thesis aimed at identifying MTBC at species level, their drug-resistance patterns, and mycobactericidal effect of different regimens in patients treated for RR/MDR-TB and drug-susceptible (DS-TB). This was a cross sectional study nested in a longitudinal design that followed patien… Show more
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