Application of Modified Pictet—Spengler Reaction for the Synthesis of Thiazolo‐ and Pyrazolo‐quinolines.

Abstract

Fused pyridine derivatives R 0450 Application of Modified Pictet-Spengler Reaction for the Synthesis of Thiazoloand Pyrazolo-quinolines. -The amines (II) and (IV) are found to be useful substrates. Their condensation with aldehydes provides a novel approach to the target compounds which are of biological interest. -(DUGGINENI, S.; SAWANT, D.; SAHA, B.; KUNDU*, B.; Tetrahedron 62 (2006) 14, 3228-3241; Div. Med. Chem., Cent. Drug Res. Inst., Lucknow 226 001, India; Eng.) -Jannicke 30-162