Application of Modern Technologies in New Ultra-High Resolution Electrocardiography Method

Zaichenko, Kirill V.; Zhmyleva, A. A.; Khrapov, Sergey O.; Logachev, Evgeny; Gurevich, Boris

doi:10.1109/usbereit48449.2020.9117664

Cited by 7 publications

(1 citation statement)

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“…In this study, we used the original method of UHR ECG, which might be superior to conventional ECG in certain aspects [18,19]. UHR ECG ensures registration and analysis of all meaningful changes of the electrical cardiac potentials using standard ECG electrodes.…”

Section: Registration Of Uhr Ecg and Signal Processingmentioning

confidence: 99%

Ultra-High-Resolution Electrocardiography Enables Earlier Detection of Transmural and Subendocardial Myocardial Ischemia Compared to Conventional Electrocardiography

Zaichenko,

Kordyukova,

Sonin

et al. 2023

Diagnostics

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The sensitivity of exercise ECG is marginally sufficient for the detection of mild reduction of coronary blood flow in patients with early coronary atherosclerosis. Here, we describe the application of a new technique of ECG registration/analysis—ultra-high-resolution ECG (UHR ECG)—for early detection of myocardial ischemia (MIS). The utility of UHR ECG vs. conventional ECG (C ECG) was tested in anesthetized rats and pigs. Transmural MIS was induced in rats by the ligation of the left coronary artery (CA). In pigs, subendocardial ischemia of a variable extent was produced by stepwise inflation of a balloon within the right CA, causing a 25–100% reduction of its lumen. In rats, a reduction in power spectral density (PSD) in the high-frequency (HF) channel of UHR ECG was registered at 60 s after ischemia (power 0.81 ± 0.14 vs. 1.25 ± 0.12 mW at baseline, p < 0.01). This was not accompanied by any ST segment elevation on C ECG. In pigs, PSD in the HF channel of UHR ECG was significantly decreased at a 25% reduction of CA lumen, while the ST segment on C ECG remained unchanged. In conclusion, UHR ECG enabled earlier detection of transmural MIS compared to C ECG. PSD in the HF channel of UHR ECG demonstrated greater sensitivity in the settings of subendocardial ischemia.

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Section: Registration Of Uhr Ecg and Signal Processingmentioning

confidence: 99%