Application of metal hemoclips for closure of endoscopic mucosal resection–induced ulcers of the stomach to prevent delayed bleeding

Choi, Kee Don; Jung, Hwoon‐Yong; Lee, Gin Hyug; Oh, Tae Hoon; Jo, Ji Yun; Song, Ho June; Hong, Seoung Soo; Kim, Jin-Ho

doi:10.1007/s00464-008-9743-0

Cited by 50 publications

(54 citation statements)

References 20 publications

(39 reference statements)

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“…The use of hemoclip systems for the adaptation of deep wall defects after endoscopic mucosal resection was [20]. The OTSC clip seems to be an appropriate method to adapt such lesions.…”

Section: Discussionmentioning

confidence: 99%

The Over-The-Scope Clip (OTSC) for the treatment of gastrointestinal bleeding, perforations, and fistulas

Subotova²,

et al. 2011

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“…The use of hemoclip systems for the adaptation of deep wall defects after endoscopic mucosal resection was [20]. The OTSC clip seems to be an appropriate method to adapt such lesions.…”

Section: Discussionmentioning

confidence: 99%

The Over-The-Scope Clip (OTSC) for the treatment of gastrointestinal bleeding, perforations, and fistulas

Subotova²,

et al. 2011

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“…147,148,241 The risk of delayed bleeding after EMR may be reduced by prophylactic closure of mucosal defects with endoscopic clips. 142,242 High-dose proton pump inhibitor therapy improves ulcer healing rates and reduces the risk of delayed bleeding after ESD. 148 Perforation caused by EMR or ESD may be managed by application of endoscopic clips and conservative measures, if identified during the initial procedure.…”

Section: Endoscopic Management Of Adverse Events Of Endoluminal Therapymentioning

confidence: 99%

Adverse events of upper GI endoscopy

Ben–Menachem¹,

Decker²,

Early³

et al. 2012

Gastrointestinal Endoscopy

289

161

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“…The EMR procedure was performed as previously described techniques. 14,15 During the procedure, eight biopsy specimens were obtained using elongated large-cup forceps (Olympus FB-24k-1; Olympus) for histologic examination of CAG: two specimens were from the lesser curvature (LC) of the antrum; two from the LC of the upper corpus; two from the greater curvature (GC) of the lower corpus; and two from the GC of the upper corpus. These four biopsy sites were chosen because H. pylori-induced gastritis progresses from the gastric angularis toward the antrum and corpus along the LC, and then involves the corporal GC upward to the fundus.…”

Section: Endoscopic Procedures and Biopsymentioning

confidence: 99%

Low Levels of Pepsinogen I and Pepsinogen I/II Ratio are Valuable Serologic Markers for Predicting Extensive Gastric Corpus Atrophy in Patients Undergoing Endoscopic Mucosectomy

et al. 2010

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Background/Aims: The levels of pepsinogen (PG) I and the PGI/II ratio are useful serologic markers for chronic atrophic gastritis. This study evaluated the performance and clinical implications of these markers in patients undergoing endoscopic mucosectomy. Methods: We enrolled 142 consecutive patients with early gastric tumors and Helicobacter pylori infection who were eligible for mucosectomy. Chronic gastritis and atrophy were assessed using four defined biopsy procedures. Serum PGs were measured by an enzyme immunoassay. Optimal diagnostic cut-offs and performance were determined using receiver operating characteristic curves. Results: The PGI level and the PGI/II ratio decreased with corpus-dominant gastritis and as atrophy advanced toward the corpus greater curvature (GC). For the presence of corpus GC atrophy, the areas under the PGI and PGI/II-ratio curves were 0.82 and 0.77, respectively. The optimal cut-off levels were 59.3μg/L for PGI (sensitivity, 83.3%; specificity, 78.4%) and 3.6μg/L for PGI/II ratio (sensitivity, 70.0%; specificity, 78.4%). Using these serologic cut-off levels, we found that the frequency of corpus tumor location differed significantly (32.9% vs 11.1% for PGI ＜59.3 and ≥59.3μg/L, respectively; and 31.1% vs 14.8% for PGI/II ratio ＜3.5 and ≥3.5, respectively; p＜0.05). Conclusions: A low PGI level and PGI/II ratio are valuable serologic markers for predicting corpus GC atrophy, and have clinical implications with respect to the corpus location of tumors in mucosectomy patients. (Gut Liver 2010;4:475-480)

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Application of metal hemoclips for closure of endoscopic mucosal resection–induced ulcers of the stomach to prevent delayed bleeding

Abstract: Prophylactic closure of gastric EMR-induced ulcers with hemoclips reduced delayed bleeding.

Cited by 50 publications

References 20 publications

The Over-The-Scope Clip (OTSC) for the treatment of gastrointestinal bleeding, perforations, and fistulas

The Over-The-Scope Clip (OTSC) for the treatment of gastrointestinal bleeding, perforations, and fistulas

Adverse events of upper GI endoscopy

Low Levels of Pepsinogen I and Pepsinogen I/II Ratio are Valuable Serologic Markers for Predicting Extensive Gastric Corpus Atrophy in Patients Undergoing Endoscopic Mucosectomy

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