Application of Magnesium Oxide Nanoparticles in Dentistry: A Literature Review

Sharifian, Seyedarsham; Loghmani, Alireza; Nayyerain, Shiva; Javanbakht, Sanaz; Daneii, Pouria

doi:10.1055/s-0042-1760673

Cited by 6 publications

(2 citation statements)

References 58 publications

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“…Moreover, there is evidence that MgO nanoparticles possess effective antilarvicidal properties [288]. Some scientific efforts have been made focusing on the use of magnesium oxide based on its antibiofilm properties [289], and the findings are quite promising in several fields, such as dentistry [290,291], and hopefully this potential of MgO will be soon exploited. Furthermore, in dentistry, the presence of MgO nanoparticles seems to reduce the corrosion resistance and compressive strength of implants; thus, they might be widely used in the near future [290,291].…”

Section: Future Prospectsmentioning

confidence: 99%

Magnesium Oxide (MgO) Nanoparticles: Synthetic Strategies and Biomedical Applications

Gatou,

Skylla,

Dourou

et al. 2024

Crystals

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In recent times, there has been considerable interest among researchers in magnesium oxide (MgO) nanoparticles, due to their excellent biocompatibility, stability, and diverse biomedical uses, such as antimicrobial, antioxidant, anticancer, and antidiabetic properties, as well as tissue engineering, bioimaging, and drug delivery applications. Consequently, the escalating utilization of magnesium oxide nanoparticles in medical contexts necessitates the in-depth exploration of these nanoparticles. Notably, existing literature lacks a comprehensive review of magnesium oxide nanoparticles’ synthesis methods, detailed biomedical applications with mechanisms, and toxicity assessments. Thus, this review aims to bridge this gap by furnishing a comprehensive insight into various synthetic approaches for the development of MgO nanoparticles. Additionally, it elucidates their noteworthy biomedical applications as well as their potential mechanisms of action, alongside summarizing their toxicity profiles. This article also highlights challenges and future prospects for further exploring MgO nanoparticles in the biomedical field. Existing literature indicates that synthesized magnesium oxide nanoparticles demonstrate substantial biocompatibility and display significant antibacterial, antifungal, anticancer, and antioxidant properties. Consequently, this review intends to enhance readers’ comprehension regarding recent advancements in synthesizing MgO nanoparticles through diverse approaches and their promising applications in biomedicine.

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Section: Future Prospectsmentioning

confidence: 99%

Magnesium Oxide (MgO) Nanoparticles: Synthetic Strategies and Biomedical Applications

Gatou,

Skylla,

Dourou

et al. 2024

Crystals

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“…The antibacterial properties of MgO NPs are of interest for medical use. The high pH of MgO NPs (alkaline pH) may contribute to their antibacterial activity [102]. Despite the complexity and unknown antibacterial mechanisms in metal oxides, the main antibacterial mechanisms for metal oxides, including Mg NPs, can be classified as follows: (1) physical damage to the bacterial cell wall as a result of the electrostatic interaction of the sharp edges of nanomaterials with the cell wall membrane; (2) the production of ROS; (3) the entrapment of bacteria in aggregated nanomaterials; (4) the disruption of bacterial glycolysis;…”

Section: Mg/mgo Nps' Biological Propertiesmentioning

confidence: 99%

Recent Advances in Magnesium–Magnesium Oxide Nanoparticle Composites for Biomedical Applications

Saberi,

Baltatu,

Vizureanu

2024

Bioengineering

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Magnesium (Mg) is considered an attractive option for orthopedic applications due to its density and elastic modulus close to the natural bone of the body, as well as biodegradability and good tensile strength. However, it faces serious challenges, including a high degradation rate and, as a result, a loss of mechanical properties during long periods of exposure to the biological environment. Also, among its other weaknesses, it can be mentioned that it does not deal with bacterial biofilms. It has been found that making composites by synergizing its various components can be an efficient way to improve its properties. Among metal oxide nanoparticles, magnesium oxide nanoparticles (MgO NPs) have distinct physicochemical and biological properties, including biocompatibility, biodegradability, high bioactivity, significant antibacterial properties, and good mechanical properties, which make it a good choice as a reinforcement in composites. However, the lack of comprehensive understanding of the effectiveness of Mg NPs as Mg matrix reinforcements in mechanical, corrosion, and biological fields is considered a challenge in their application. While introducing the role of MgO NPs in medical fields, this article summarizes the most important results of recent research on the mechanical, corrosion, and biological performance of Mg/MgO composites.

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Noninvasive assessment of novel nanohybrid resin cement adaptation using cross-polarization optical coherence tomography

Naguib,

Bakhsh,

Mazhar

et al. 2024

Dental Materials

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Application of Magnesium Oxide Nanoparticles in Dentistry: A Literature Review

Cited by 6 publications

References 58 publications

Magnesium Oxide (MgO) Nanoparticles: Synthetic Strategies and Biomedical Applications

Magnesium Oxide (MgO) Nanoparticles: Synthetic Strategies and Biomedical Applications

Recent Advances in Magnesium–Magnesium Oxide Nanoparticle Composites for Biomedical Applications

Noninvasive assessment of novel nanohybrid resin cement adaptation using cross-polarization optical coherence tomography

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