“…Molecular methods, such as polymerase chain reaction (PCR) and all its variants, DNA microarray, as well as tissue-print and dot-blot hybridization, have high sensitivities and reasonable costs [ 75 , 77 , 78 ]. Nevertheless, current and innovative techniques, such as metagenomics high-throughput sequencing (HTS), CRISPR/Cas12, or machine learning (ML) approaches, have created a revolution in the detection of multiple viruses that are either known or unknown [ 79 , 80 , 81 ].…”