Application of luminescence for estimating the efficiency of photocatalysts

Mitochondrial activity of cancer and normal mesenchymal stem cells in vitro cultured in medium with different deuterium content

“…But due to the higher strength of carbon-deuterium (C-D) chemical bonds compared with carbon-protium (C-H), the properties of deuterated compounds change, for example, the reaction rates with their participation are reduced [3]. Recently, significant experimental material has been accumulated on the effect of the deuterium/protium (D/H) ratio in water on processes involving biologically active substances in vitro and in vivo [4][5][6][7][8][9][10][11][12][13][14]. It was noted that the kinetics of biological reactions depends on the ratio of deuterium/protium (D/H) in aqueous solutions.…”

“…It was noted that the kinetics of biological reactions depends on the ratio of deuterium/protium (D/H) in aqueous solutions. It was found that in the range of deuterium content below natural concentrations (<150 ppm, deuterium depleted water) (ddw), the kinetic isotope effect (KIE) of biologically active compounds increases [6,15]. In such medium, the rates of dissolution of substances [16] and mutarotation of carbohydrates [17], the optical properties of chiral compounds [10,15] change, the absorption and accumulation of ions of essential trace elements in medicinal and food plants increase [18].…”