Application of low-level laser radiation with TiO₂, Ag/TiO₂ and S/TiO₂ on Streptococcus salivarius isolated from the oral cavity

Abstract

In our research, we determine the effect of low-level laser irradiation with nanoparticles on Streptococcus salivarius. Photodynamic killing of periodontopathogenic bacteria may be an alternative to the systemic application of antibacterial drugs used in the treatment of periodontal diseases. The application of photosensitizing nanoparticles and their excitation by visible light of blue spectra enables effective killing of periodontopathogens. This data combined with the results demonstrates that TiO2, AgTiO2 and S/TiO2 can inhibit the proliferation of Streptococcus salivarius due to its high photocatalytic activity, which irreversibly damages the cell walls and membranes.

Enhancement of the Antibacterial Efficiency of Silver Nanoparticles against Gram-Positive and Gram-Negative Bacteria Using Blue Laser Light

“…Panas et al [19] reported that excitation of Ag/TiO 2 NPs by blue laser light at 455 nm for 5 min inhibited the proliferation of Streptococcus salivarius due to high photocatalytic activity that irreversibly damages cell walls and membranes. In another study, Fuertes et al [20] analyzed the antibacterial activity of Ag-NPs coated with porous silica and irradiated at their SPR frequency of 387 nm, which induced production of toxic ROS and subsequent cell death in E. coli.…”