Application of ionic liquids in the microwave-assisted extraction of trans-resveratrol from Rhizma Polygoni Cuspidati

Du, Fuyou; Xiao, Xiaohua; Li, Gongke

doi:10.1016/j.chroma.2006.11.049

Cited by 193 publications

(109 citation statements)

References 28 publications

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“…Ionic liquid [Bmim]Br was suited to extract trans-resveratrol efficiently because of its strong interaction with trans-resveratrol. These multi-interactions of ionic charge and a hydrogen bond between the ionic component and trans-resveratrol resulting in the higher dissolution of trans-resveratrol (Du et al, 2007). By increasing the concentration of the IL solution, it's also increasing the extraction yield.…”

Section: Optimum Extraction Parametersmentioning

confidence: 99%

“…Besides that, the IL 1-n-butyl-3-methylimidazolium ([Bmim]Br) solution has been published that it successfully extracted transresveratrol from Polygoni cuspidatum (Du et al, 2007). There has not been found studies that reporting on optimization of resveratrol extraction methods from Gnetum gnemon L. (Melinjo) using MAE method and comparison the extraction efficacy of both organic solvent and [Bmim] Br.…”

Section: Introductionmentioning

confidence: 99%

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Comparison of Ionic Liquid-Microwave-Assisted Extraction and MAE of Resveratrol from Melinjo (Gnetum gnemon L.) Seeds

Rachmawati

Ayuningtyas

Mun’im³

2017

J App Pharm Sci

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Purpose: This study investigated the effect of [Bmim]Br microwave assisted extraction (MAE), and MAE methods using ethanol on trans-resveratrol extraction from Melinjo (Gnetum gnemon) seeds. Methods: The three-level response surface methodology was used to optimize extraction conditions for transresveratrol content from Melinjo seeds using MAE method and IL-MAE. Resveratrol content was determined using HPLC, and antioxidant activity was examined by DPPH assay. Results: Compared to the MAE-ethanol method, then the optimum result of IL-MAE was reached with [Bmim]Br concentration 2.5 mol/L; microwave power 10%; and extraction time 10 min with the trans-resveratrol value 0.52 mg/g. The antioxidant activity value of IL-MAE melinjo seed extract was in 82.82% of DPPH inhibition. Conclusion: This IL-MAE method was suitable to apply as an alternative technique to extract the active compound from the plant.

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Section: Optimum Extraction Parametersmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Comparison of Ionic Liquid-Microwave-Assisted Extraction and MAE of Resveratrol from Melinjo (Gnetum gnemon L.) Seeds

Rachmawati

Ayuningtyas

Mun’im³

2017

J App Pharm Sci

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“…Table 2, and chromatographic profile had shown in Figure 3. Whilst the HPTLC fingerprinting of each extract using non-conventional extraction method with [BMIM] Br as a solvent showed a total of 8,9,12,9,10,8,9,9,8,10,8,8,5,7,8,13,9,9,12,8,10,8,9,9,12,12,10,10,13, and 10 peaks were observed at 254 nm and a total of 5,6,6,5,4,6,3,5,5,3,4,5,4,4,5,5,5,6,5,5,5,…”

Section: Determination Of Hptlc Fingerprinting Profilementioning

confidence: 99%

“…(using 1-butyl-3-methyl-imidazolium bromide [BMIM] Br). 3 Alkaloid phenolic (Liensinine, Isoliensinine, and Neferine) from Nelumbo nucifera Graerthn (using 1-butyl-3-methylimidazolium tetrafluoroborate [BMIM]BF 4 ). 4 Piperine from Piper ningrum (using [BMIM]BF 4 ).…”

Section: Introductionmentioning

confidence: 99%

Application of Ionic Liquid based Microwave-Assisted Extraction of the Secondary Metabolite from Peperomia pellucida (L) Kunth

Ahmad

Yanuar²,

Mulia³

et al. 2017

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Introduction: An ionic liquid (ILs) is a new alternative solvent (containing cations and anions) has the physical and specific solutions properties, and also had proven to be a promising substituent of conventional organic solvents are flammable, volatile and toxic in various processes. The ILS application in separating the secondary metabolites compound from Peperomia pellucida (L) Kunth herbaceous can be carried out using microwaveassisted extraction method (MAE). Objective: The aim of this study was to investigate the effect of ionic liquid based microwave-assisted extraction method for attracting the secondary metabolites compound from P. pellucida compared with a conventional solvent for the enrichment of secondary metabolites (especially polyphenols group) and their HPTLC fingerprinting profile. Methods: The herb dried powder extracted by microwave-assisted extraction using an ionic liquid such us 1-Butyl-3-methylimidazolium chloride ([BMIM]Cl), 1-Butyl-3-methylimidazolium Bromide ([BMIM]Br). The obtained extract solution was partitioned using an organic solvent; the extract was evaporated to obtain a dry extract and determination the HPTLC fingerprinting profile. Results: Based on the research results was obtained from the various types of solvents there are differences in the extraction of secondary metabolite.

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“…Water was added as modifier to diethyl ether and ethanol or water can be added into poor microwave absorber such as hexane to enhance microwave heating efficiency (Alfaro et al, 2003;Ku et al, 2007). Room temperature ionic liquids interest lies in their negligible vapor pressure, wide thermal range in the liquid state, good thermal stability, tunable viscosity, miscibility with water and organic solvents, good solubility and extractability for various organic compounds (Du et al, 2007). Mixing carbonyl iron powders with the moist sample may increase absorption of microwave energy, particularly where solvent is limited (such as in SFMAE by Wang et al, 2006).…”

Section: Optimisation Of Microwave-assisted Extraction (Mae)mentioning

confidence: 99%

Quality Preservation and Cost Effectiveness in the Extraction of Nutraceutically-Relevant Fractions from Microbial and Vegetal Matrices

Bravi¹,

Cicci²,

Torzillo³

2012

Scientific, Health and Social Aspects of the Food Industry

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Terrestrial and microbial vegetal matrices are a major source of nutraceutically and pharmaceutically relevant chemical compounds of different nature. In several cases the consumption of the raw vegetal or microbial matrix has been part of established diet regimes and has provided the consumers with a host of once unknown dietary benefits. Nowadays, while the consumption of the raw matrix still provides the original functional value, the separation of bioactive-enriched fractions has enabled the production of nutraceuticals, while the addition of nutraceutical fractions to food previously lacking or partially possessing them has lead to the industrial production of functionalised or fortified food respectively. The separability of nutraceutically relevant fractions depends on the combination of several different features of the carrier matrix and of the fraction to be separated, namely: size, aggregation state and physical (hardness) and chemical (composition) features of the embodying matrix, chemical nature, bonding and degree of dispersion of the fraction of interest in the embodying matrix. Physical, chemical and electrostatic interactions between the embodying matrix, the fractions to be separated and exogenous agents (equipment and process auxiliary substances, and the environment) affect the desired separation; the chemical nature of the solvent (if any), the specific energy applied by the physical agent (if any), the frequency and intensity of the mechanical (e.g., ultrasound) and electromagnetic (e.g., microwave) field (if any), the processing time and temperature and the presence of specific case-by-case unwanted substances (e.g., water, oxygen, metal ions) play a role in the final outcome of the recovery process of the desired fraction

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Application of ionic liquids in the microwave-assisted extraction of trans-resveratrol from Rhizma Polygoni Cuspidati

Cited by 193 publications

References 28 publications

Comparison of Ionic Liquid-Microwave-Assisted Extraction and MAE of Resveratrol from Melinjo (Gnetum gnemon L.) Seeds

Comparison of Ionic Liquid-Microwave-Assisted Extraction and MAE of Resveratrol from Melinjo (Gnetum gnemon L.) Seeds

Application of Ionic Liquid based Microwave-Assisted Extraction of the Secondary Metabolite from Peperomia pellucida (L) Kunth

Quality Preservation and Cost Effectiveness in the Extraction of Nutraceutically-Relevant Fractions from Microbial and Vegetal Matrices

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